Immune Phenotypic Characterization of a TRAIL-Knockout Mouse

Immune Phenotypic Characterization of a TRAIL-Knockout Mouse

The TNF-superfamily member TRAIL is known to mediate selective apoptosis in tumor cells suggesting this protein as a potential antitumor drug target. However, initial successful pr-clinical results could not be translated into the clinic. Reasons for the ineffectiveness of TRAIL-targeting in tumor t...

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Bibliographic Details
Main Authors: Ani K. Stoyanova, Arne Sattler, Elisabeth M. Hahn, Nina A. Hering, Marco Arndt, Johannes Christian Lauscher, Fiona Speichinger-Hillenberg, Katja Kotsch, Ann-Kathrin Berg, Katharina Beyer
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
TRAIL: immunological phenotype
lymphocytes
dendritic cells
knockout mouse
Online Access:https://www.mdpi.com/2072-6694/15/5/1475

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