Mechanical properties and sustainable bacterial resistance effect of strontium-modified phosphate-based glass microfiller in dental composite resins
Abstract Dental composite resins are widely used in dental restorations. However, their clinical application is limited by the occurrence of secondary caries. Strontium-modified phosphate-based glass (Sr-PBG) is a material known to have a sustainable bacterial resistance effect. The mechanical prope...
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Nature Portfolio
2023-10-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-44490-z |
| _version_ | 1797577017484378112 |
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| author | Hye-Bin Go Myung-Jin Lee Ji-Young Seo Sung-Yun Byun Jae-Sung Kwon |
| author_facet | Hye-Bin Go Myung-Jin Lee Ji-Young Seo Sung-Yun Byun Jae-Sung Kwon |
| author_sort | Hye-Bin Go |
| collection | DOAJ |
| description | Abstract Dental composite resins are widely used in dental restorations. However, their clinical application is limited by the occurrence of secondary caries. Strontium-modified phosphate-based glass (Sr-PBG) is a material known to have a sustainable bacterial resistance effect. The mechanical properties (in particular, flexural strength, modulus of elasticity, and hardness) of dental materials determine their function. Therefore, this study aimed to investigate the mechanical and ion-releasing properties as well as the sustainable bacterial resistance effect of bioactive resin composites containing Sr-PBG. The data were analyzed by ANOVA and Tuckey’s tests (p < 0.05). We incorporated a Sr-PBG microfiller at 3, 6, and 9 wt.% concentrations into a commercially available composite resin and investigated the mechanical properties (flexural strength, elastic modulus, and micro hardness), ion release characteristics, and color of the resultant resins. In addition, we examined the antibacterial effects of the composite resins against Streptococcus mutans (S. mutans). The mechanical properties of the Sr-PBG groups differed only slightly from those of the control group (p > 0.05). However, the optical density at 600 nm of S. mutans incubated on the experimental group was significantly lower compared to that observed with the control (p < 0.05) both before and after thermocycling between 5 and 55 ℃ for 850 cycles (dwell time: 45 s). Therefore, strontium-modified resin materials exhibited a sustainable bacterial resistance effect in vitro while maintaining some of the mechanical properties of ordinary acrylic resins. |
| first_indexed | 2024-03-10T22:01:58Z |
| format | Article |
| id | doaj.art-09586a63d1ec4ae3966e372577934c50 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-10T22:01:58Z |
| publishDate | 2023-10-01 |
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| series | Scientific Reports |
| spelling | doaj.art-09586a63d1ec4ae3966e372577934c502023-11-19T12:54:20ZengNature PortfolioScientific Reports2045-23222023-10-0113111110.1038/s41598-023-44490-zMechanical properties and sustainable bacterial resistance effect of strontium-modified phosphate-based glass microfiller in dental composite resinsHye-Bin Go0Myung-Jin Lee1Ji-Young Seo2Sung-Yun Byun3Jae-Sung Kwon4Department and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of DentistryDepartment of Dental Hygiene, Division of Health Science, Baekseok UniversityDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of DentistryDepartment and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of DentistryDepartment and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of DentistryAbstract Dental composite resins are widely used in dental restorations. However, their clinical application is limited by the occurrence of secondary caries. Strontium-modified phosphate-based glass (Sr-PBG) is a material known to have a sustainable bacterial resistance effect. The mechanical properties (in particular, flexural strength, modulus of elasticity, and hardness) of dental materials determine their function. Therefore, this study aimed to investigate the mechanical and ion-releasing properties as well as the sustainable bacterial resistance effect of bioactive resin composites containing Sr-PBG. The data were analyzed by ANOVA and Tuckey’s tests (p < 0.05). We incorporated a Sr-PBG microfiller at 3, 6, and 9 wt.% concentrations into a commercially available composite resin and investigated the mechanical properties (flexural strength, elastic modulus, and micro hardness), ion release characteristics, and color of the resultant resins. In addition, we examined the antibacterial effects of the composite resins against Streptococcus mutans (S. mutans). The mechanical properties of the Sr-PBG groups differed only slightly from those of the control group (p > 0.05). However, the optical density at 600 nm of S. mutans incubated on the experimental group was significantly lower compared to that observed with the control (p < 0.05) both before and after thermocycling between 5 and 55 ℃ for 850 cycles (dwell time: 45 s). Therefore, strontium-modified resin materials exhibited a sustainable bacterial resistance effect in vitro while maintaining some of the mechanical properties of ordinary acrylic resins.https://doi.org/10.1038/s41598-023-44490-z |
| spellingShingle | Hye-Bin Go Myung-Jin Lee Ji-Young Seo Sung-Yun Byun Jae-Sung Kwon Mechanical properties and sustainable bacterial resistance effect of strontium-modified phosphate-based glass microfiller in dental composite resins Scientific Reports |
| title | Mechanical properties and sustainable bacterial resistance effect of strontium-modified phosphate-based glass microfiller in dental composite resins |
| title_full | Mechanical properties and sustainable bacterial resistance effect of strontium-modified phosphate-based glass microfiller in dental composite resins |
| title_fullStr | Mechanical properties and sustainable bacterial resistance effect of strontium-modified phosphate-based glass microfiller in dental composite resins |
| title_full_unstemmed | Mechanical properties and sustainable bacterial resistance effect of strontium-modified phosphate-based glass microfiller in dental composite resins |
| title_short | Mechanical properties and sustainable bacterial resistance effect of strontium-modified phosphate-based glass microfiller in dental composite resins |
| title_sort | mechanical properties and sustainable bacterial resistance effect of strontium modified phosphate based glass microfiller in dental composite resins |
| url | https://doi.org/10.1038/s41598-023-44490-z |
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