Severe Type of Minocycline-Induced Hyperpigmentation Mimicking Peripheral Arterial Occlusive Disease in a Bullous Pemphigoid Patient
Minocycline is a tetracycline group antibiotic that is known to cause significant antibacterial and anti-inflammatory effects. Minocycline has been widely used to treat systemic infection, acne, dermatitis, and rosacea. However, various dose-related side effects of hyperpigmentation in whole body tis...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-07-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/8/3/93 |
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| author | Meng-Yu Wu Yueh-Tseng Hou Giou-Teng Yiang Andy Po-Yi Tsai Ching-Hsiang Lin |
| author_facet | Meng-Yu Wu Yueh-Tseng Hou Giou-Teng Yiang Andy Po-Yi Tsai Ching-Hsiang Lin |
| author_sort | Meng-Yu Wu |
| collection | DOAJ |
| description | Minocycline is a tetracycline group antibiotic that is known to cause significant antibacterial and anti-inflammatory effects. Minocycline has been widely used to treat systemic infection, acne, dermatitis, and rosacea. However, various dose-related side effects of hyperpigmentation in whole body tissues have been reported. Three main types of minocycline-induced hyperpigmentation have been identified. In rare severe hyperpigmentation cases, drug-induced hyperpigmentation can mimic local cellulitis or peripheral arterial occlusive disease (PAOD). These processes require different therapeutic strategies. Therefore, early diagnosis is extremely important for physicians to determine the etiology of the hyperpigmentation, and subsequently discontinue the minocycline if indicated. We describe a rare case presenting a severe form of type III minocycline-induced hyperpigmentation mimicking peripheral arterial occlusive disease in a bullous pemphigoid patient. |
| first_indexed | 2024-12-11T07:30:52Z |
| format | Article |
| id | doaj.art-09598e86cebc49de894b952d5edd3394 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-12-11T07:30:52Z |
| publishDate | 2019-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-09598e86cebc49de894b952d5edd33942022-12-22T01:15:50ZengMDPI AGAntibiotics2079-63822019-07-01839310.3390/antibiotics8030093antibiotics8030093Severe Type of Minocycline-Induced Hyperpigmentation Mimicking Peripheral Arterial Occlusive Disease in a Bullous Pemphigoid PatientMeng-Yu Wu0Yueh-Tseng Hou1Giou-Teng Yiang2Andy Po-Yi Tsai3Ching-Hsiang Lin4Department of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, TaiwanDepartment of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, TaiwanDepartment of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, TaiwanDepartment of Medical Research, Buddhist Tzu Chi General Hospital, Hualien 970, TaiwanDepartment of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, TaiwanMinocycline is a tetracycline group antibiotic that is known to cause significant antibacterial and anti-inflammatory effects. Minocycline has been widely used to treat systemic infection, acne, dermatitis, and rosacea. However, various dose-related side effects of hyperpigmentation in whole body tissues have been reported. Three main types of minocycline-induced hyperpigmentation have been identified. In rare severe hyperpigmentation cases, drug-induced hyperpigmentation can mimic local cellulitis or peripheral arterial occlusive disease (PAOD). These processes require different therapeutic strategies. Therefore, early diagnosis is extremely important for physicians to determine the etiology of the hyperpigmentation, and subsequently discontinue the minocycline if indicated. We describe a rare case presenting a severe form of type III minocycline-induced hyperpigmentation mimicking peripheral arterial occlusive disease in a bullous pemphigoid patient.https://www.mdpi.com/2079-6382/8/3/93hyperpigmentationminocyclineperipheral arterial occlusive diseasebullous pemphigoid |
| spellingShingle | Meng-Yu Wu Yueh-Tseng Hou Giou-Teng Yiang Andy Po-Yi Tsai Ching-Hsiang Lin Severe Type of Minocycline-Induced Hyperpigmentation Mimicking Peripheral Arterial Occlusive Disease in a Bullous Pemphigoid Patient Antibiotics hyperpigmentation minocycline peripheral arterial occlusive disease bullous pemphigoid |
| title | Severe Type of Minocycline-Induced Hyperpigmentation Mimicking Peripheral Arterial Occlusive Disease in a Bullous Pemphigoid Patient |
| title_full | Severe Type of Minocycline-Induced Hyperpigmentation Mimicking Peripheral Arterial Occlusive Disease in a Bullous Pemphigoid Patient |
| title_fullStr | Severe Type of Minocycline-Induced Hyperpigmentation Mimicking Peripheral Arterial Occlusive Disease in a Bullous Pemphigoid Patient |
| title_full_unstemmed | Severe Type of Minocycline-Induced Hyperpigmentation Mimicking Peripheral Arterial Occlusive Disease in a Bullous Pemphigoid Patient |
| title_short | Severe Type of Minocycline-Induced Hyperpigmentation Mimicking Peripheral Arterial Occlusive Disease in a Bullous Pemphigoid Patient |
| title_sort | severe type of minocycline induced hyperpigmentation mimicking peripheral arterial occlusive disease in a bullous pemphigoid patient |
| topic | hyperpigmentation minocycline peripheral arterial occlusive disease bullous pemphigoid |
| url | https://www.mdpi.com/2079-6382/8/3/93 |
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