The preemptive effect of tramadol and metamizole on the intensity of postoperative pain

Aim To demonstrate the analgesic effect of preemptively administered tramadol and metamizole on the postoperative pain severity, after an elective operative hysterectomy with adnexectomy. Methods There were three groups with 30 patients in each group. Patients included in the study were between 45...

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Main Authors: Ismet Suljević, Muamer Hadžiavdić, Ismana Šurković, Omer Suljević, Maida Turan, Ehlimana Mušija
Format: Article
Language:English
Published: Medical Association of Zenica-Doboj Canton 2020-08-01
Series:Medicinski Glasnik
Subjects:
Online Access:http://ljkzedo.ba/mgpdf/mg33/18_Suljevic_1118_A.pdf
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author Ismet Suljević
Muamer Hadžiavdić
Ismana Šurković
Omer Suljević
Maida Turan
Ehlimana Mušija
author_facet Ismet Suljević
Muamer Hadžiavdić
Ismana Šurković
Omer Suljević
Maida Turan
Ehlimana Mušija
author_sort Ismet Suljević
collection DOAJ
description Aim To demonstrate the analgesic effect of preemptively administered tramadol and metamizole on the postoperative pain severity, after an elective operative hysterectomy with adnexectomy. Methods There were three groups with 30 patients in each group. Patients included in the study were between 45 to 67 years old. They were all in the ASA group II. Randomization was performed in random order according to the regular elective operating program. Patients in Group I received i. m. tramadol 1mg/kg, and in Group II 30mg/kg of metamizole, five minutes before anaesthesia induction. Patients did not receive preemptive analgesia in Group III (control). All patients underwent the same induction anaesthesiology procedure with propofol, fentanyl, tracrium, supplemented with O2, N2O, and sevoflurane at an appropriate dose until MAC 1 was reached. Surgeries lasted for 80-120 minutes. Every patient performed a resting pain assessment 30 minutes after an extubation by Numerical Pain Scale (NPS). Results We found out that tramadol had a better effect in preemptive analgesia and that the average pain score for Group I was 6.10 (p=0.043). In Group II, it was 7.93 (p=0.022). There is significant difference in pain intensity between patients in the control group, (pain intensity was 9.16), and those who received tramadol and metamizole. There was no significant difference in the intensity of pain when using these two analgesics (p=0.733). Conclusion The effect of preemptively administered tramadol prior to the introduction of general anaesthesia in postoperative pain is significantly more favourable than the effect of metamizole.
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spelling doaj.art-095a33d20d03471797028bb3f08e50c92022-12-22T01:39:24ZengMedical Association of Zenica-Doboj CantonMedicinski Glasnik1840-01321840-24452020-08-0117228528910.17392/1118-20The preemptive effect of tramadol and metamizole on the intensity of postoperative painIsmet Suljević0Muamer Hadžiavdić1Ismana Šurković2Omer Suljević3Maida Turan4Ehlimana Mušija5Clinic for Anaesthesia and Resuscitation, Clinical Centre of University of Sarajevo, Bosnia and HerzegovinaClinic for Bone Surgery, Clinical Centre of University of Sarajevo, Bosnia and HerzegovinaDepartment for Endocrinology, Diabetes, and Diseases of Metabolism; Clinical Centre of University of Sarajevo, Bosnia and HerzegovinaSarajevo Health Centre, Bosnia and HerzegovinaHealthcare Group Acibadem, Representative Office in Sarajevo, Bosnia and HerzegovinaClinic for Heart Diseases and Rheumatism, Clinical Centre of University of Sarajevo; Sarajevo, Bosnia and HerzegovinaAim To demonstrate the analgesic effect of preemptively administered tramadol and metamizole on the postoperative pain severity, after an elective operative hysterectomy with adnexectomy. Methods There were three groups with 30 patients in each group. Patients included in the study were between 45 to 67 years old. They were all in the ASA group II. Randomization was performed in random order according to the regular elective operating program. Patients in Group I received i. m. tramadol 1mg/kg, and in Group II 30mg/kg of metamizole, five minutes before anaesthesia induction. Patients did not receive preemptive analgesia in Group III (control). All patients underwent the same induction anaesthesiology procedure with propofol, fentanyl, tracrium, supplemented with O2, N2O, and sevoflurane at an appropriate dose until MAC 1 was reached. Surgeries lasted for 80-120 minutes. Every patient performed a resting pain assessment 30 minutes after an extubation by Numerical Pain Scale (NPS). Results We found out that tramadol had a better effect in preemptive analgesia and that the average pain score for Group I was 6.10 (p=0.043). In Group II, it was 7.93 (p=0.022). There is significant difference in pain intensity between patients in the control group, (pain intensity was 9.16), and those who received tramadol and metamizole. There was no significant difference in the intensity of pain when using these two analgesics (p=0.733). Conclusion The effect of preemptively administered tramadol prior to the introduction of general anaesthesia in postoperative pain is significantly more favourable than the effect of metamizole.http://ljkzedo.ba/mgpdf/mg33/18_Suljevic_1118_A.pdfanalgesiageneral anaesthesiahysterectomypain assessment
spellingShingle Ismet Suljević
Muamer Hadžiavdić
Ismana Šurković
Omer Suljević
Maida Turan
Ehlimana Mušija
The preemptive effect of tramadol and metamizole on the intensity of postoperative pain
Medicinski Glasnik
analgesia
general anaesthesia
hysterectomy
pain assessment
title The preemptive effect of tramadol and metamizole on the intensity of postoperative pain
title_full The preemptive effect of tramadol and metamizole on the intensity of postoperative pain
title_fullStr The preemptive effect of tramadol and metamizole on the intensity of postoperative pain
title_full_unstemmed The preemptive effect of tramadol and metamizole on the intensity of postoperative pain
title_short The preemptive effect of tramadol and metamizole on the intensity of postoperative pain
title_sort preemptive effect of tramadol and metamizole on the intensity of postoperative pain
topic analgesia
general anaesthesia
hysterectomy
pain assessment
url http://ljkzedo.ba/mgpdf/mg33/18_Suljevic_1118_A.pdf
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