Aldosterone-to-renin ratio (ARR) as a screening tool for primary aldosteronism (PA)

Aldosterone-to-renin ratio (ARR) as a screening tool for primary aldosteronism (PA)

The aldosterone-to-renin ratio (ARR) is the standard screening test for primary aldosteronism (PA). Because of the poor reproducibility of the ARR, repeat testing is recommended if the result is not compatible with the clinical condition. Various methods to measure renin are used in different hospit...

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Bibliographic Details
Main Authors: Chia-Hung Lin, Ching-Han Lin, Mu-Chi Chung, Chi-Sheng Hung, Fen-Yu Tseng, Leay Kiaw Er, Charles Jia-Yin Hou, Yen-Hung Lin, Vin-Cent Wu, Hao-Min Cheng, Hsien-Li Kao, Kwan-Dun Wu, Tai-Shuan Lai
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Journal of the Formosan Medical Association
Subjects:
Primary aldosteronism
Screening
Aldosterone-to-renin ratio
Renin
Aldosterone
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664623001456
Description
Summary:The aldosterone-to-renin ratio (ARR) is the standard screening test for primary aldosteronism (PA). Because of the poor reproducibility of the ARR, repeat testing is recommended if the result is not compatible with the clinical condition. Various methods to measure renin are used in different hospitals in Taiwan, and the ARR cutoff values also differ among laboratories. The Task Force of Taiwan PA recommend using plasma renin activity (PRA) to calculate ARR instead of direct renin concentration (DRC) unless PRA is unavailable, because PRA is widely used in international guidelines and most studies.
ISSN:0929-6646

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