Streptococcus mutans PrsA mediates AtlA secretion contributing to extracellular DNA release and biofilm formation in the pathogenesis of infective endocarditis

Streptococcus mutans PrsA mediates AtlA secretion contributing to extracellular DNA release and biofilm formation in the pathogenesis of infective endocarditis

The role of secretion chaperone-regulated virulence proteins in the pathogenesis of infective endocarditis (IE) induced by viridans streptococci such as Streptococcus mutans is unclear. In this study, we investigated the contribution of the foldase protein PrsA, a putative parvulin-type peptidyl-pro...

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Bibliographic Details
Main Authors: Chih-Chieh Hsu, Ron-Bin Hsu, Xoong-Harng Oon, Ya-Tang Chen, Jeng-Wei Chen, Che-Hao Hsu, Yu-Min Kuo, Yi-Hsien Shih, Jean-San Chia, Chiau-Jing Jung
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Virulence
Subjects:
Streptococcus mutans
infective endocarditis
PrsA
AtlA
extracellular DNA
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2022.2105351

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