Potential anti-tumor effects of regulatory T cells in the tumor microenvironment: a review

Potential anti-tumor effects of regulatory T cells in the tumor microenvironment: a review

Abstract Regulatory T cells (Tregs) expressing the transcription factor FoxP3 are essential for maintaining immunological balance and are a significant component of the immunosuppressive tumor microenvironment (TME). Single-cell RNA sequencing (ScRNA-seq) technology has shown that Tregs exhibit sign...

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Bibliographic Details
Main Authors: Yu Li, Cangang Zhang, Aimin Jiang, Anqi Lin, Zaoqu Liu, Xiangshu Cheng, Wanting Wang, Quan Cheng, Jian Zhang, Ting Wei, Peng Luo
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Subjects:
Tregs
Heterogeneity
Fragility
Anti-tumor effects
Immunotherapy
Online Access:https://doi.org/10.1186/s12967-024-05104-y

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