Transposable elements in TDP-43-mediated neurodegenerative disorders.

Transposable elements in TDP-43-mediated neurodegenerative disorders.

Elevated expression of specific transposable elements (TEs) has been observed in several neurodegenerative disorders. TEs also can be active during normal neurogenesis. By mining a series of deep sequencing datasets of protein-RNA interactions and of gene expression profiles, we uncovered extensive...

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Bibliographic Details
Main Authors:	Wanhe Li, Ying Jin, Lisa Prazak, Molly Hammell, Josh Dubnau
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3434193?pdf=render

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