Transposable elements in TDP-43-mediated neurodegenerative disorders.
Elevated expression of specific transposable elements (TEs) has been observed in several neurodegenerative disorders. TEs also can be active during normal neurogenesis. By mining a series of deep sequencing datasets of protein-RNA interactions and of gene expression profiles, we uncovered extensive...
Prif Awduron: | Wanhe Li, Ying Jin, Lisa Prazak, Molly Hammell, Josh Dubnau |
---|---|
Fformat: | Erthygl |
Iaith: | English |
Cyhoeddwyd: |
Public Library of Science (PLoS)
2012-01-01
|
Cyfres: | PLoS ONE |
Mynediad Ar-lein: | http://europepmc.org/articles/PMC3434193?pdf=render |
Eitemau Tebyg
-
Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS.
gan: Lisa Krug, et al.
Cyhoeddwyd: (2017-03-01) -
Propagation of TDP-43 proteinopathy in neurodegenerative disorders
gan: Rachel Keszycki, et al.
Cyhoeddwyd: (2022-01-01) -
Conformational Enigma of TDP-43 Misfolding in Neurodegenerative Disorders
gan: Meenakshi Pillai, et al.
Cyhoeddwyd: (2024-09-01) -
TDP-43 pathology in Drosophila induces glial-cell type specific toxicity that can be ameliorated by knock-down of SF2/SRSF1.
gan: Sarah Krupp, et al.
Cyhoeddwyd: (2023-09-01) -
Endogenous retroviruses and TDP-43 proteinopathy form a sustaining feedback driving intercellular spread of Drosophila neurodegeneration
gan: Yung-Heng Chang, et al.
Cyhoeddwyd: (2023-02-01)