Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico
Background Knowledge about the influence of early developmental factors on cardiometabolic health in the Maya is limited.Aim To analyse the relationship between birthweight (BW) and cardiometabolic parameters in a sample of rural Maya children from Yucatan, Mexico.Subjects and methods We took anthro...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Annals of Human Biology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/03014460.2024.2323037 |
| _version_ | 1826919874573631488 |
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| author | Julio Lara-Riegos Hugo Azcorra Juan Carlos Salazar-Rendón Víctor Arana-Argáez María Teresa Castillo-Burguete Nina Mendez-Dominguez |
| author_facet | Julio Lara-Riegos Hugo Azcorra Juan Carlos Salazar-Rendón Víctor Arana-Argáez María Teresa Castillo-Burguete Nina Mendez-Dominguez |
| author_sort | Julio Lara-Riegos |
| collection | DOAJ |
| description | Background Knowledge about the influence of early developmental factors on cardiometabolic health in the Maya is limited.Aim To analyse the relationship between birthweight (BW) and cardiometabolic parameters in a sample of rural Maya children from Yucatan, Mexico.Subjects and methods We took anthropometric measurements and obtained data on BW and fasting blood samples in a sample of 75 children aged 5–14 years. Dependent variables were: fat mass index (FMI), body mass index (BMI), glucose (G), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), LDL/HDL and TC/HDL ratios and metabolic index (TGxG/HDL2). Outcomes were transformed to y = 100 log(e)x and the resulting estimates are interpreted as symmetrical percentage differences. The main independent variable was BW z-score. Multiple linear regression analyses were used to assess the relationship between BW and outcomes.Results An increase of one standard deviation in BW predicted 6.6% (95% CI [–11.6, −1.6]) decrease in HDL and 11% (95% CI [3.7, 18.4]), 7.8% (95% CI [2.3, 13.2]) and 19.6% (95% CI [3.1, 36]) increases in LDL/HDL, TC/HDL and metabolic index, respectively.Conclusion Higher birthweights were associated with adverse levels of biochemical parameters in this sample of rural Maya children. |
| first_indexed | 2024-04-25T00:07:39Z |
| format | Article |
| id | doaj.art-096c44a30a7f46a489d671f5a10e6376 |
| institution | Directory Open Access Journal |
| issn | 0301-4460 1464-5033 |
| language | English |
| last_indexed | 2025-02-17T13:20:51Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Human Biology |
| spelling | doaj.art-096c44a30a7f46a489d671f5a10e63762024-12-26T09:21:16ZengTaylor & Francis GroupAnnals of Human Biology0301-44601464-50332024-12-0151110.1080/03014460.2024.2323037Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, MexicoJulio Lara-Riegos0Hugo Azcorra1Juan Carlos Salazar-Rendón2Víctor Arana-Argáez3María Teresa Castillo-Burguete4Nina Mendez-Dominguez5Laboratorio de Bioquímica y Genética Molecular, Facultad de Química de la Universidad Autónoma de Yucatán, Mérida, MéxicoCentro de Investigaciones Silvio Zavala, Universidad Modelo, Mérida, MéxicoDirección de Nutrición y Enfermedades Crónicas, Secretaría de Salud, Mérida, MéxicoLaboratorio de Farmacología, Facultad de Química de la Universidad Autónoma de Yucatán, Mérida, MéxicoCentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mérida, MéxicoHospital Regional de Alta Especialidad de la Península de Yucatán, Mérida, MéxicoBackground Knowledge about the influence of early developmental factors on cardiometabolic health in the Maya is limited.Aim To analyse the relationship between birthweight (BW) and cardiometabolic parameters in a sample of rural Maya children from Yucatan, Mexico.Subjects and methods We took anthropometric measurements and obtained data on BW and fasting blood samples in a sample of 75 children aged 5–14 years. Dependent variables were: fat mass index (FMI), body mass index (BMI), glucose (G), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), LDL/HDL and TC/HDL ratios and metabolic index (TGxG/HDL2). Outcomes were transformed to y = 100 log(e)x and the resulting estimates are interpreted as symmetrical percentage differences. The main independent variable was BW z-score. Multiple linear regression analyses were used to assess the relationship between BW and outcomes.Results An increase of one standard deviation in BW predicted 6.6% (95% CI [–11.6, −1.6]) decrease in HDL and 11% (95% CI [3.7, 18.4]), 7.8% (95% CI [2.3, 13.2]) and 19.6% (95% CI [3.1, 36]) increases in LDL/HDL, TC/HDL and metabolic index, respectively.Conclusion Higher birthweights were associated with adverse levels of biochemical parameters in this sample of rural Maya children.https://www.tandfonline.com/doi/10.1080/03014460.2024.2323037Birthweightcardiometabolic healthMayaYucatanMexico |
| spellingShingle | Julio Lara-Riegos Hugo Azcorra Juan Carlos Salazar-Rendón Víctor Arana-Argáez María Teresa Castillo-Burguete Nina Mendez-Dominguez Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico Annals of Human Biology Birthweight cardiometabolic health Maya Yucatan Mexico |
| title | Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico |
| title_full | Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico |
| title_fullStr | Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico |
| title_full_unstemmed | Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico |
| title_short | Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico |
| title_sort | birthweight and its association with cardiometabolic risk parameters in rural maya children from yucatan mexico |
| topic | Birthweight cardiometabolic health Maya Yucatan Mexico |
| url | https://www.tandfonline.com/doi/10.1080/03014460.2024.2323037 |
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