Effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmons
Aim. To assess the effect of cytoflavin on the dynamics of the blood and oral fluid prooxidant-antioxidant system in patients with maxillofacial area phlegmons.Materials and methods. 55 patients were included in the study. The patients were divided into three groups: control group (group 1, n = 20);...
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| Format: | Article |
| Language: | Russian |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2020-02-01
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| Series: | Кубанский научный медицинский вестник |
| Subjects: | |
| Online Access: | https://ksma.elpub.ru/jour/article/view/2069 |
| _version_ | 1797295386362118144 |
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| author | Tatiana V. Gaivoronskaya Oksana V. Shvets Svetlana K. Shafranova |
| author_facet | Tatiana V. Gaivoronskaya Oksana V. Shvets Svetlana K. Shafranova |
| author_sort | Tatiana V. Gaivoronskaya |
| collection | DOAJ |
| description | Aim. To assess the effect of cytoflavin on the dynamics of the blood and oral fluid prooxidant-antioxidant system in patients with maxillofacial area phlegmons.Materials and methods. 55 patients were included in the study. The patients were divided into three groups: control group (group 1, n = 20); comparison group (group 2, n = 15); patients with phlegmons of the maxillofacial area (group 3, n = 20). As part of therapy, the patients in group 3 were additionally receiving cytoflavin (10 ml cytoflavin in 200 ml saline solution, 1 time per day, for 6 days). The treatment and monitoring was performed over the period of 6 days, during which the blood and oral fluid indicators were estimated 4 times (day 1, 2, 4 and 6).Results. Cytoflavin had a positive effect on the state of the prooxidant-antioxidant balance in patients with maxillofacial area phlegmons. In comparison with the control group, patients in group 3 demonstrated a lower content of oxidative modifi cation products and a higher antioxidant activity of blood plasma. Cytoflavin therapy also led to an increase in the activity of glutathione peroxidase and reductase, as well as an increase in the concentration of glutathione at the last stage of the therapy.Conclusion. The obtained data indicate the potential of cytoflavin as part of complex metabolic therapy for patients with purulent inflammatory processes of the maxillofacial area. |
| first_indexed | 2024-03-07T21:47:05Z |
| format | Article |
| id | doaj.art-096d320763934fa1ab1ef9954d2a89f1 |
| institution | Directory Open Access Journal |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| last_indexed | 2024-03-07T21:47:05Z |
| publishDate | 2020-02-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj.art-096d320763934fa1ab1ef9954d2a89f12024-02-25T10:57:24ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442020-02-01271182610.25207/1608-6228-2020-27-1-18-261158Effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmonsTatiana V. Gaivoronskaya0Oksana V. Shvets1Svetlana K. Shafranova2Kuban State Medical UniversityKuban State Medical UniversityKuban State Medical UniversityAim. To assess the effect of cytoflavin on the dynamics of the blood and oral fluid prooxidant-antioxidant system in patients with maxillofacial area phlegmons.Materials and methods. 55 patients were included in the study. The patients were divided into three groups: control group (group 1, n = 20); comparison group (group 2, n = 15); patients with phlegmons of the maxillofacial area (group 3, n = 20). As part of therapy, the patients in group 3 were additionally receiving cytoflavin (10 ml cytoflavin in 200 ml saline solution, 1 time per day, for 6 days). The treatment and monitoring was performed over the period of 6 days, during which the blood and oral fluid indicators were estimated 4 times (day 1, 2, 4 and 6).Results. Cytoflavin had a positive effect on the state of the prooxidant-antioxidant balance in patients with maxillofacial area phlegmons. In comparison with the control group, patients in group 3 demonstrated a lower content of oxidative modifi cation products and a higher antioxidant activity of blood plasma. Cytoflavin therapy also led to an increase in the activity of glutathione peroxidase and reductase, as well as an increase in the concentration of glutathione at the last stage of the therapy.Conclusion. The obtained data indicate the potential of cytoflavin as part of complex metabolic therapy for patients with purulent inflammatory processes of the maxillofacial area.https://ksma.elpub.ru/jour/article/view/2069phlegmoncytoflavinmaxillofacial areaantioxidant systemglutathione |
| spellingShingle | Tatiana V. Gaivoronskaya Oksana V. Shvets Svetlana K. Shafranova Effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmons Кубанский научный медицинский вестник phlegmon cytoflavin maxillofacial area antioxidant system glutathione |
| title | Effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmons |
| title_full | Effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmons |
| title_fullStr | Effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmons |
| title_full_unstemmed | Effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmons |
| title_short | Effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmons |
| title_sort | effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmons |
| topic | phlegmon cytoflavin maxillofacial area antioxidant system glutathione |
| url | https://ksma.elpub.ru/jour/article/view/2069 |
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