Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth Movement
Optical vibrational techniques show a high potentiality in many biomedical fields for their characteristics of high sensitivity in revealing detailed information on composition, structure, and molecular interaction with reduced analysis time. In the last years, we have used these techniques for inve...
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| Format: | Article |
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MDPI AG
2021-04-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/7/1405 |
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| author | Fabrizia d’Apuzzo Ludovica Nucci Ines Delfino Marianna Portaccio Giuseppe Minervini Gaetano Isola Ismene Serino Carlo Camerlingo Maria Lepore |
| author_facet | Fabrizia d’Apuzzo Ludovica Nucci Ines Delfino Marianna Portaccio Giuseppe Minervini Gaetano Isola Ismene Serino Carlo Camerlingo Maria Lepore |
| author_sort | Fabrizia d’Apuzzo |
| collection | DOAJ |
| description | Optical vibrational techniques show a high potentiality in many biomedical fields for their characteristics of high sensitivity in revealing detailed information on composition, structure, and molecular interaction with reduced analysis time. In the last years, we have used these techniques for investigating gingival crevicular fluid (GCF) and periodontal ligament (PDL) during orthodontic tooth treatment. The analysis with Raman and infrared signals of GCF and PDL samples highlighted that different days of orthodontic force application causes modifications in the molecular secondary structure at specific wavenumbers related to the Amide I, Amide III, CH deformation, and CH<sub>3</sub>/CH<sub>2</sub>. In the present review, we report the most relevant results and a brief description of the experimental techniques and data analysis procedure in order to evidence that the vibrational spectroscopies could be a potential useful tool for an immediate monitoring of the individual patient’s response to the orthodontic tooth movement, aiming to more personalized treatment reducing any side effects. |
| first_indexed | 2024-03-10T12:43:09Z |
| format | Article |
| id | doaj.art-096db9e5237449809b8de356f8b5a96f |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T12:43:09Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-096db9e5237449809b8de356f8b5a96f2023-11-21T13:42:04ZengMDPI AGJournal of Clinical Medicine2077-03832021-04-01107140510.3390/jcm10071405Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth MovementFabrizia d’Apuzzo0Ludovica Nucci1Ines Delfino2Marianna Portaccio3Giuseppe Minervini4Gaetano Isola5Ismene Serino6Carlo Camerlingo7Maria Lepore8Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, 80138 Napoli, ItalyMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, 80138 Napoli, ItalyDepartment of Ecological and Biological Sciences, University of Tuscia, 01100 Viterbo, ItalyDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Napoli, ItalyMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, 80138 Napoli, ItalyDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, 95124 Catania, ItalyDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Napoli, ItalyCNR-SPIN, SuPerconductivity and Other INnovative Materials and Devices Institute, 80078 Pozzuoli, ItalyDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Napoli, ItalyOptical vibrational techniques show a high potentiality in many biomedical fields for their characteristics of high sensitivity in revealing detailed information on composition, structure, and molecular interaction with reduced analysis time. In the last years, we have used these techniques for investigating gingival crevicular fluid (GCF) and periodontal ligament (PDL) during orthodontic tooth treatment. The analysis with Raman and infrared signals of GCF and PDL samples highlighted that different days of orthodontic force application causes modifications in the molecular secondary structure at specific wavenumbers related to the Amide I, Amide III, CH deformation, and CH<sub>3</sub>/CH<sub>2</sub>. In the present review, we report the most relevant results and a brief description of the experimental techniques and data analysis procedure in order to evidence that the vibrational spectroscopies could be a potential useful tool for an immediate monitoring of the individual patient’s response to the orthodontic tooth movement, aiming to more personalized treatment reducing any side effects.https://www.mdpi.com/2077-0383/10/7/1405vibrational spectroscopiesRaman spectroscopiesinfrared spectroscopiesorthodontic tooth movementgingival crevicular fluidperiodontal ligament |
| spellingShingle | Fabrizia d’Apuzzo Ludovica Nucci Ines Delfino Marianna Portaccio Giuseppe Minervini Gaetano Isola Ismene Serino Carlo Camerlingo Maria Lepore Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth Movement Journal of Clinical Medicine vibrational spectroscopies Raman spectroscopies infrared spectroscopies orthodontic tooth movement gingival crevicular fluid periodontal ligament |
| title | Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth Movement |
| title_full | Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth Movement |
| title_fullStr | Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth Movement |
| title_full_unstemmed | Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth Movement |
| title_short | Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth Movement |
| title_sort | application of vibrational spectroscopies in the qualitative analysis of gingival crevicular fluid and periodontal ligament during orthodontic tooth movement |
| topic | vibrational spectroscopies Raman spectroscopies infrared spectroscopies orthodontic tooth movement gingival crevicular fluid periodontal ligament |
| url | https://www.mdpi.com/2077-0383/10/7/1405 |
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