Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review
This study aimed to describe the prevalence of comorbidities associated with chronic obstructive pulmonary disease (COPD) and their relation with relevant outcomes. A systematic review based on the PRISMA methodology was performed from January 2020 until July 2021. The MEDLINE, Lilacs, and Scielo da...
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| Format: | Article |
| Language: | English |
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The Korean Academy of Tuberculosis and Respiratory Diseases
2022-07-01
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| Series: | Tuberculosis and Respiratory Diseases |
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| Online Access: | http://e-trd.org/upload/pdf/trd-2021-0179.pdf |
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| author | Natasha Cordeiro dos Santos Marc Miravitlles Aquiles Assunção Camelier Victor Durier Cavalcanti de Almeida Roberto Rodrigues Bandeira Tosta Maciel Fernanda Warken Rosa Camelier |
| author_facet | Natasha Cordeiro dos Santos Marc Miravitlles Aquiles Assunção Camelier Victor Durier Cavalcanti de Almeida Roberto Rodrigues Bandeira Tosta Maciel Fernanda Warken Rosa Camelier |
| author_sort | Natasha Cordeiro dos Santos |
| collection | DOAJ |
| description | This study aimed to describe the prevalence of comorbidities associated with chronic obstructive pulmonary disease (COPD) and their relation with relevant outcomes. A systematic review based on the PRISMA methodology was performed from January 2020 until July 2021. The MEDLINE, Lilacs, and Scielo databases were searched to identify studies related to COPD and its comorbidities. Observational studies on the prevalence of comorbidities in COPD patients and costs with health estimates, reduced quality of life, and mortality were included. Studies that were restricted to one or more COPD pain assessments and only specific comorbidities such as osteoporosis, bronchitis, and asthma were excluded. The initial search identified 1,409 studies and after applying the inclusion and exclusion criteria, 20 studies were finally selected for analysis (comprising data from 447,459 COPD subjects). The most frequent COPD comorbidities were: hypertension (range, 17%–64.7%), coronary artery disease (19.9%–47.8%), diabetes (10.2%–45%), osteoarthritis (18%–43.8%), psychiatric conditions (12.1%–33%), and asthma (14.7%–32.5%). Several comorbidities had an impact on the frequency and severity of COPD exacerbations, quality of life, and mortality risk, in particular malignancies, coronary artery disease, chronic heart failure, and cardiac arrhythmias. Comorbidities, especially cardiovascular diseases and diabetes, are frequent in COPD patients, and some of them are associated with higher mortality. |
| first_indexed | 2024-12-11T05:44:40Z |
| format | Article |
| id | doaj.art-096ea1d3afeb423387c27d9f0f449a6d |
| institution | Directory Open Access Journal |
| issn | 1738-3536 2005-6184 |
| language | English |
| last_indexed | 2024-12-11T05:44:40Z |
| publishDate | 2022-07-01 |
| publisher | The Korean Academy of Tuberculosis and Respiratory Diseases |
| record_format | Article |
| series | Tuberculosis and Respiratory Diseases |
| spelling | doaj.art-096ea1d3afeb423387c27d9f0f449a6d2022-12-22T01:19:00ZengThe Korean Academy of Tuberculosis and Respiratory DiseasesTuberculosis and Respiratory Diseases1738-35362005-61842022-07-0185320522010.4046/trd.2021.01794784Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic ReviewNatasha Cordeiro dos Santos0Marc Miravitlles1Aquiles Assunção Camelier2Victor Durier Cavalcanti de Almeida3Roberto Rodrigues Bandeira Tosta Maciel4Fernanda Warken Rosa Camelier5 Department of Life Sciences, State University of Bahia (UNEB), Bahia, Brazil Department of Pneumology, Hospital Vall d’Hebron/Vall d’Hebron Research institute (VHIR), Barcelona, Spain Department of Life Sciences, State University of Bahia (UNEB), Bahia, Brazil Department of Life Sciences, State University of Bahia (UNEB), Bahia, Brazil Department of Life Sciences, State University of Bahia (UNEB), Bahia, Brazil Department of Life Sciences, State University of Bahia (UNEB), Bahia, BrazilThis study aimed to describe the prevalence of comorbidities associated with chronic obstructive pulmonary disease (COPD) and their relation with relevant outcomes. A systematic review based on the PRISMA methodology was performed from January 2020 until July 2021. The MEDLINE, Lilacs, and Scielo databases were searched to identify studies related to COPD and its comorbidities. Observational studies on the prevalence of comorbidities in COPD patients and costs with health estimates, reduced quality of life, and mortality were included. Studies that were restricted to one or more COPD pain assessments and only specific comorbidities such as osteoporosis, bronchitis, and asthma were excluded. The initial search identified 1,409 studies and after applying the inclusion and exclusion criteria, 20 studies were finally selected for analysis (comprising data from 447,459 COPD subjects). The most frequent COPD comorbidities were: hypertension (range, 17%–64.7%), coronary artery disease (19.9%–47.8%), diabetes (10.2%–45%), osteoarthritis (18%–43.8%), psychiatric conditions (12.1%–33%), and asthma (14.7%–32.5%). Several comorbidities had an impact on the frequency and severity of COPD exacerbations, quality of life, and mortality risk, in particular malignancies, coronary artery disease, chronic heart failure, and cardiac arrhythmias. Comorbidities, especially cardiovascular diseases and diabetes, are frequent in COPD patients, and some of them are associated with higher mortality.http://e-trd.org/upload/pdf/trd-2021-0179.pdfcopdcomorbidityseverityhospitalizationhealthcare xostsmortality |
| spellingShingle | Natasha Cordeiro dos Santos Marc Miravitlles Aquiles Assunção Camelier Victor Durier Cavalcanti de Almeida Roberto Rodrigues Bandeira Tosta Maciel Fernanda Warken Rosa Camelier Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review Tuberculosis and Respiratory Diseases copd comorbidity severity hospitalization healthcare xosts mortality |
| title | Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review |
| title_full | Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review |
| title_fullStr | Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review |
| title_full_unstemmed | Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review |
| title_short | Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review |
| title_sort | prevalence and impact of comorbidities in individuals with chronic obstructive pulmonary disease a systematic review |
| topic | copd comorbidity severity hospitalization healthcare xosts mortality |
| url | http://e-trd.org/upload/pdf/trd-2021-0179.pdf |
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