Evaluating conditions for the formation of chitosan/gelatin microparticles
Chitosan/gelatin microparticles were prepared by complex coacervation. Three chitosan (CH) samples, with different acetylation degrees and intrinsic viscosities, were used together with commercial gelatin (G) samples. Microparticles formation was investigated at various CH/G ratios, within the pH ra...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Polímeros
2009-06-01
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| Series: | Polímeros |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282009000200010 |
| _version_ | 1819267392882081792 |
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| author | Marcia C. Silva Cristina T. Andrade |
| author_facet | Marcia C. Silva Cristina T. Andrade |
| author_sort | Marcia C. Silva |
| collection | DOAJ |
| description | Chitosan/gelatin microparticles were prepared by complex coacervation. Three chitosan (CH) samples, with different acetylation degrees and intrinsic viscosities, were used together with commercial gelatin (G) samples. Microparticles formation was investigated at various CH/G ratios, within the pH range of 3.5 to 6.0. Reactions were carried out at 40 and 60 ºC, for 2, 4, and 6 hours. Turbidity measurements performed at 633 nm were used to monitor the process. The resulting curves revealed maximum values, which were correlated to the glucosamine content of CH samples. After isolation, yields were determined, and the microparticles were characterized by infrared spectroscopy (FTIR) and thermogravimetry (TGA). Both techniques evidenced the formation of coacervate microparticles. The highest yields in microparticles were determined for the system comprising the CH sample with the lowest degree of acetylation and intrinsic viscosity, and the gelatin sample with the lowest bloom strength. |
| first_indexed | 2024-12-23T21:16:27Z |
| format | Article |
| id | doaj.art-0970e49f75e045fb8676ddf0dd2bdae9 |
| institution | Directory Open Access Journal |
| issn | 0104-1428 1678-5169 |
| language | English |
| last_indexed | 2024-12-23T21:16:27Z |
| publishDate | 2009-06-01 |
| publisher | Associação Brasileira de Polímeros |
| record_format | Article |
| series | Polímeros |
| spelling | doaj.art-0970e49f75e045fb8676ddf0dd2bdae92022-12-21T17:30:53ZengAssociação Brasileira de PolímerosPolímeros0104-14281678-51692009-06-0119213313710.1590/S0104-14282009000200010Evaluating conditions for the formation of chitosan/gelatin microparticlesMarcia C. SilvaCristina T. AndradeChitosan/gelatin microparticles were prepared by complex coacervation. Three chitosan (CH) samples, with different acetylation degrees and intrinsic viscosities, were used together with commercial gelatin (G) samples. Microparticles formation was investigated at various CH/G ratios, within the pH range of 3.5 to 6.0. Reactions were carried out at 40 and 60 ºC, for 2, 4, and 6 hours. Turbidity measurements performed at 633 nm were used to monitor the process. The resulting curves revealed maximum values, which were correlated to the glucosamine content of CH samples. After isolation, yields were determined, and the microparticles were characterized by infrared spectroscopy (FTIR) and thermogravimetry (TGA). Both techniques evidenced the formation of coacervate microparticles. The highest yields in microparticles were determined for the system comprising the CH sample with the lowest degree of acetylation and intrinsic viscosity, and the gelatin sample with the lowest bloom strength.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282009000200010Chitosangelatinmicroparticlescoacervation |
| spellingShingle | Marcia C. Silva Cristina T. Andrade Evaluating conditions for the formation of chitosan/gelatin microparticles Polímeros Chitosan gelatin microparticles coacervation |
| title | Evaluating conditions for the formation of chitosan/gelatin microparticles |
| title_full | Evaluating conditions for the formation of chitosan/gelatin microparticles |
| title_fullStr | Evaluating conditions for the formation of chitosan/gelatin microparticles |
| title_full_unstemmed | Evaluating conditions for the formation of chitosan/gelatin microparticles |
| title_short | Evaluating conditions for the formation of chitosan/gelatin microparticles |
| title_sort | evaluating conditions for the formation of chitosan gelatin microparticles |
| topic | Chitosan gelatin microparticles coacervation |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282009000200010 |
| work_keys_str_mv | AT marciacsilva evaluatingconditionsfortheformationofchitosangelatinmicroparticles AT cristinatandrade evaluatingconditionsfortheformationofchitosangelatinmicroparticles |