The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway

Bibliographic Details
Main Authors: Wang Jiafang, Feng Yankun, Qi Zhong, Li Jin, Chen Zhijun, Zhang Jinming, Zhu Degang
Format: Article
Language:English
Published: De Gruyter 2024-01-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2022-0816
_version_ 1797323432518483968
author Wang Jiafang
Feng Yankun
Qi Zhong
Li Jin
Chen Zhijun
Zhang Jinming
Zhu Degang
author_facet Wang Jiafang
Feng Yankun
Qi Zhong
Li Jin
Chen Zhijun
Zhang Jinming
Zhu Degang
author_sort Wang Jiafang
collection DOAJ
first_indexed 2024-03-08T05:28:36Z
format Article
id doaj.art-09780ab007c6417390a5e3e035f23132
institution Directory Open Access Journal
issn 2391-5412
language English
last_indexed 2024-03-08T05:28:36Z
publishDate 2024-01-01
publisher De Gruyter
record_format Article
series Open Life Sciences
spelling doaj.art-09780ab007c6417390a5e3e035f231322024-02-06T09:08:15ZengDe GruyterOpen Life Sciences2391-54122024-01-0119179380010.1515/biol-2022-0816The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathwayWang Jiafang0Feng Yankun1Qi Zhong2Li Jin3Chen Zhijun4Zhang Jinming5Zhu Degang6Department of Anesthesiology, Wuhan No. 1 Hospital, No. 215 Zhongshan Avenue, Qiaokou District, Wuhan, Hubei, 430022, ChinaDepartment of Anesthesiology, Wuhan No. 1 Hospital, No. 215 Zhongshan Avenue, Qiaokou District, Wuhan, Hubei, 430022, ChinaDepartment of Anesthesiology, Wuhan No. 1 Hospital, No. 215 Zhongshan Avenue, Qiaokou District, Wuhan, Hubei, 430022, ChinaDepartment of Anesthesiology, Wuhan No. 1 Hospital, No. 215 Zhongshan Avenue, Qiaokou District, Wuhan, Hubei, 430022, ChinaDepartment of Anesthesiology, Wuhan No. 1 Hospital, No. 215 Zhongshan Avenue, Qiaokou District, Wuhan, Hubei, 430022, ChinaHubei Provincial Key Laboratory for Applied Toxicology, Hubei Center for Disease Control and Prevention, No. 35 Zhuodaoquan North Road, Hongshan District, Wuhan430079, ChinaDepartment of Anesthesiology, Wuhan No. 1 Hospital, No. 215 Zhongshan Avenue, Qiaokou District, Wuhan, Hubei, 430022, Chinahttps://doi.org/10.1515/biol-2022-0816remifentanilesketaminepain managementcamkⅱglun2bopioids
spellingShingle Wang Jiafang
Feng Yankun
Qi Zhong
Li Jin
Chen Zhijun
Zhang Jinming
Zhu Degang
The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway
Open Life Sciences
remifentanil
esketamine
pain management
camkⅱ
glun2b
opioids
title The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway
title_full The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway
title_fullStr The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway
title_full_unstemmed The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway
title_short The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway
title_sort role and mechanism of esketamine in preventing and treating remifentanil induced hyperalgesia based on the nmda receptor camkii pathway
topic remifentanil
esketamine
pain management
camkⅱ
glun2b
opioids
url https://doi.org/10.1515/biol-2022-0816
work_keys_str_mv AT wangjiafang theroleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT fengyankun theroleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT qizhong theroleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT lijin theroleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT chenzhijun theroleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT zhangjinming theroleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT zhudegang theroleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT wangjiafang roleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT fengyankun roleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT qizhong roleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT lijin roleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT chenzhijun roleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT zhangjinming roleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway
AT zhudegang roleandmechanismofesketamineinpreventingandtreatingremifentanilinducedhyperalgesiabasedonthenmdareceptorcamkiipathway