Melatonin alleviates brain and peripheral tissue edema in a neonatal rat model of hypoxic-ischemic brain damage: the involvement of edema related proteins

Melatonin alleviates brain and peripheral tissue edema in a neonatal rat model of hypoxic-ischemic brain damage: the involvement of edema related proteins

Abstract Background Previous studies have indicated edema may be involved in the pathophysiology following hypoxic-ischemic encephalopathy (HIE), and melatonin may exhibit neuro-protection against brain insults. However, little is known regarding the mechanisms that involve the protective effects of...

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Bibliographic Details
Main Authors:	Li-Xiao Xu, Yuan Lv, Yan-Hong Li, Xin Ding, Ying Wang, Xing Han, Ming-Hua Liu, Bin Sun, Xing Feng
Format:	Article
Language:	English
Published:	BMC 2017-03-01
Series:	BMC Pediatrics
Subjects:	Melatonin Hypoxic-ischemic encephalopathy Edema Aquaporin-4 Zonula occludens-1 Occludin
Online Access:	http://link.springer.com/article/10.1186/s12887-017-0824-x

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