USP30: protector of peroxisomes and mitochondria
In our recent publication, we describe a mechanism by which peroxisomes are protected from degradation by autophagy under basal conditions. Taking a page from mitophagy, peroxisomes also recruit the mitochondria deubiquitinating enzyme USP30 to counter the action of PEX2, the peroxisomal E3 ubiquiti...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2019-05-01
|
| Series: | Molecular & Cellular Oncology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/23723556.2019.1600350 |
| _version_ | 1797677123572334592 |
|---|---|
| author | Victoria Riccio G. Angus McQuibban Peter Kijun Kim |
| author_facet | Victoria Riccio G. Angus McQuibban Peter Kijun Kim |
| author_sort | Victoria Riccio |
| collection | DOAJ |
| description | In our recent publication, we describe a mechanism by which peroxisomes are protected from degradation by autophagy under basal conditions. Taking a page from mitophagy, peroxisomes also recruit the mitochondria deubiquitinating enzyme USP30 to counter the action of PEX2, the peroxisomal E3 ubiquitin ligase to regulate pexophagy. |
| first_indexed | 2024-03-11T22:40:25Z |
| format | Article |
| id | doaj.art-097a0d0e08344f3096ac103694491f3c |
| institution | Directory Open Access Journal |
| issn | 2372-3556 |
| language | English |
| last_indexed | 2024-03-11T22:40:25Z |
| publishDate | 2019-05-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Molecular & Cellular Oncology |
| spelling | doaj.art-097a0d0e08344f3096ac103694491f3c2023-09-22T09:11:00ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562019-05-016310.1080/23723556.2019.16003501600350USP30: protector of peroxisomes and mitochondriaVictoria Riccio0G. Angus McQuibban1Peter Kijun Kim2University of TorontoUniversity of TorontoUniversity of TorontoIn our recent publication, we describe a mechanism by which peroxisomes are protected from degradation by autophagy under basal conditions. Taking a page from mitophagy, peroxisomes also recruit the mitochondria deubiquitinating enzyme USP30 to counter the action of PEX2, the peroxisomal E3 ubiquitin ligase to regulate pexophagy.http://dx.doi.org/10.1080/23723556.2019.1600350mitophagypexophagy |
| spellingShingle | Victoria Riccio G. Angus McQuibban Peter Kijun Kim USP30: protector of peroxisomes and mitochondria Molecular & Cellular Oncology mitophagy pexophagy |
| title | USP30: protector of peroxisomes and mitochondria |
| title_full | USP30: protector of peroxisomes and mitochondria |
| title_fullStr | USP30: protector of peroxisomes and mitochondria |
| title_full_unstemmed | USP30: protector of peroxisomes and mitochondria |
| title_short | USP30: protector of peroxisomes and mitochondria |
| title_sort | usp30 protector of peroxisomes and mitochondria |
| topic | mitophagy pexophagy |
| url | http://dx.doi.org/10.1080/23723556.2019.1600350 |
| work_keys_str_mv | AT victoriariccio usp30protectorofperoxisomesandmitochondria AT gangusmcquibban usp30protectorofperoxisomesandmitochondria AT peterkijunkim usp30protectorofperoxisomesandmitochondria |