Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome – description of two cases
Systemic sclerosis (Ssc) is an autoimmune connective tissue disease of unknown origin, characterized by progressive fibrosis of the skin and internal organs. Immune reactions taking part in Ssc pathogenesis may contribute to cancer development; therefore patients with risk factors for this disease...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2016-06-01
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| Series: | Rheumatology |
| Subjects: | |
| Online Access: | http://www.termedia.pl/Scleroderma-of-geriatric-age-and-scleroderma-like-paraneoplastic-syndrome-description-of-two-cases,18,27674,1,1.html |
| _version_ | 1818118363734343680 |
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| author | Magdalena Marek Robert Rudny |
| author_facet | Magdalena Marek Robert Rudny |
| author_sort | Magdalena Marek |
| collection | DOAJ |
| description | Systemic sclerosis (Ssc) is an autoimmune connective tissue disease of unknown origin, characterized by progressive fibrosis of the skin and internal organs.
Immune reactions taking part in Ssc pathogenesis may contribute to cancer development; therefore patients with risk factors for this disease require observation for a neoplastic process. On the other hand, symptoms of Ssc may be a mask of various cancers. Differentiating between the idiopathic form of Ssc and scleroderma-like paraneoplastic syndrome often causes a lot of difficulties.
The article presents two cases of Ssc at the beginning of the disease after 60 years of age. The first case was diagnosed as Ssc, whereas in the second case the defined diagnosis was scleroderma-like syndrome in the course of colorectal cancer. This paper presents an analysis of differential diagnostic procedures which were performed and led to the final diagnosis, mentions types of cancers co-occurring with Ssc and suggests a screening scheme for cancer development in patients with a diagnosis of Ssc. |
| first_indexed | 2024-12-11T04:53:07Z |
| format | Article |
| id | doaj.art-097af98232244e5da8d8f313b13a8c4e |
| institution | Directory Open Access Journal |
| issn | 0034-6233 2084-9834 |
| language | English |
| last_indexed | 2024-12-11T04:53:07Z |
| publishDate | 2016-06-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Rheumatology |
| spelling | doaj.art-097af98232244e5da8d8f313b13a8c4e2022-12-22T01:20:19ZengTermedia Publishing HouseRheumatology0034-62332084-98342016-06-01542919410.5114/reum.2016.6022027674Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome – description of two casesMagdalena MarekRobert RudnySystemic sclerosis (Ssc) is an autoimmune connective tissue disease of unknown origin, characterized by progressive fibrosis of the skin and internal organs. Immune reactions taking part in Ssc pathogenesis may contribute to cancer development; therefore patients with risk factors for this disease require observation for a neoplastic process. On the other hand, symptoms of Ssc may be a mask of various cancers. Differentiating between the idiopathic form of Ssc and scleroderma-like paraneoplastic syndrome often causes a lot of difficulties. The article presents two cases of Ssc at the beginning of the disease after 60 years of age. The first case was diagnosed as Ssc, whereas in the second case the defined diagnosis was scleroderma-like syndrome in the course of colorectal cancer. This paper presents an analysis of differential diagnostic procedures which were performed and led to the final diagnosis, mentions types of cancers co-occurring with Ssc and suggests a screening scheme for cancer development in patients with a diagnosis of Ssc.http://www.termedia.pl/Scleroderma-of-geriatric-age-and-scleroderma-like-paraneoplastic-syndrome-description-of-two-cases,18,27674,1,1.htmlcancer scleroderma paraneoplastic syndrome |
| spellingShingle | Magdalena Marek Robert Rudny Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome – description of two cases Rheumatology cancer scleroderma paraneoplastic syndrome |
| title | Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome – description of two cases |
| title_full | Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome – description of two cases |
| title_fullStr | Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome – description of two cases |
| title_full_unstemmed | Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome – description of two cases |
| title_short | Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome – description of two cases |
| title_sort | scleroderma of geriatric age and scleroderma like paraneoplastic syndrome description of two cases |
| topic | cancer scleroderma paraneoplastic syndrome |
| url | http://www.termedia.pl/Scleroderma-of-geriatric-age-and-scleroderma-like-paraneoplastic-syndrome-description-of-two-cases,18,27674,1,1.html |
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