Reappraisal on pharmacological and mechanical treatments of heart failure

Abstract Heart failure (HF) is a highly frequent disorder with considerable morbidity, hospitalization, and mortality; thus, it invariably places pressure on clinical and public health systems in the modern world. There have been notable advances in the definition, diagnosis, and treatment of HF, an...

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Main Authors: Bo Liang, Yu-Xiu Zhao, Xiao-Xiao Zhang, Hui-Ling Liao, Ning Gu
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12933-020-01024-5
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author Bo Liang
Yu-Xiu Zhao
Xiao-Xiao Zhang
Hui-Ling Liao
Ning Gu
author_facet Bo Liang
Yu-Xiu Zhao
Xiao-Xiao Zhang
Hui-Ling Liao
Ning Gu
author_sort Bo Liang
collection DOAJ
description Abstract Heart failure (HF) is a highly frequent disorder with considerable morbidity, hospitalization, and mortality; thus, it invariably places pressure on clinical and public health systems in the modern world. There have been notable advances in the definition, diagnosis, and treatment of HF, and newly developed agents and devices have been widely adopted in clinical practice. Here, this review first summarizes the current emerging therapeutic agents, including pharmacotherapy, device-based therapy, and the treatment of some common comorbidities, to improve the prognosis of HF patients. Then, we discuss and point out the commonalities and areas for improvement in current clinical studies of HF. Finally, we highlight the gaps in HF research. We are looking forward to a bright future with reduced morbidity and mortality from HF.
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spelling doaj.art-097ddb7e64904fafa1a2221c749c6e082022-12-22T01:08:46ZengBMCCardiovascular Diabetology1475-28402020-05-0119111810.1186/s12933-020-01024-5Reappraisal on pharmacological and mechanical treatments of heart failureBo Liang0Yu-Xiu Zhao1Xiao-Xiao Zhang2Hui-Ling Liao3Ning Gu4Nanjing University of Chinese MedicineHospital (T.C.M.) Affiliated to Southwest Medical UniversityNanjing University of Chinese MedicineHospital (T.C.M.) Affiliated to Southwest Medical UniversityNanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineAbstract Heart failure (HF) is a highly frequent disorder with considerable morbidity, hospitalization, and mortality; thus, it invariably places pressure on clinical and public health systems in the modern world. There have been notable advances in the definition, diagnosis, and treatment of HF, and newly developed agents and devices have been widely adopted in clinical practice. Here, this review first summarizes the current emerging therapeutic agents, including pharmacotherapy, device-based therapy, and the treatment of some common comorbidities, to improve the prognosis of HF patients. Then, we discuss and point out the commonalities and areas for improvement in current clinical studies of HF. Finally, we highlight the gaps in HF research. We are looking forward to a bright future with reduced morbidity and mortality from HF.http://link.springer.com/article/10.1186/s12933-020-01024-5Heart failurePharmacotherapyDevicesTreatmentManagementPrognosis
spellingShingle Bo Liang
Yu-Xiu Zhao
Xiao-Xiao Zhang
Hui-Ling Liao
Ning Gu
Reappraisal on pharmacological and mechanical treatments of heart failure
Cardiovascular Diabetology
Heart failure
Pharmacotherapy
Devices
Treatment
Management
Prognosis
title Reappraisal on pharmacological and mechanical treatments of heart failure
title_full Reappraisal on pharmacological and mechanical treatments of heart failure
title_fullStr Reappraisal on pharmacological and mechanical treatments of heart failure
title_full_unstemmed Reappraisal on pharmacological and mechanical treatments of heart failure
title_short Reappraisal on pharmacological and mechanical treatments of heart failure
title_sort reappraisal on pharmacological and mechanical treatments of heart failure
topic Heart failure
Pharmacotherapy
Devices
Treatment
Management
Prognosis
url http://link.springer.com/article/10.1186/s12933-020-01024-5
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