Prevalence and risk factors of osteoporosis in Saudi end-stage renal disease patients on hemodialysis
Background: Osteoporosis is characterized by a decrease in bone mineral density, thereby increasing the risk of pathological fractures. It is a common complication of chronic kidney disease. However, there is limited local data on the prevalence of osteoporosis in end-stage renal disease. Objective:...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Saudi Journal of Medicine and Medical Sciences |
| Subjects: | |
| Online Access: | http://www.sjmms.net/article.asp?issn=1658-631X;year=2022;volume=10;issue=3;spage=259;epage=265;aulast=Mahzari |
| _version_ | 1797991255707222016 |
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| author | Moeber M Mahzari Ahmed R Alibrahim Nawaf A Alghamdi Muatassem A Alsadhan Saad M Almoamary Emad M Masuadi Awad S Al Shahrani |
| author_facet | Moeber M Mahzari Ahmed R Alibrahim Nawaf A Alghamdi Muatassem A Alsadhan Saad M Almoamary Emad M Masuadi Awad S Al Shahrani |
| author_sort | Moeber M Mahzari |
| collection | DOAJ |
| description | Background: Osteoporosis is characterized by a decrease in bone mineral density, thereby increasing the risk of pathological fractures. It is a common complication of chronic kidney disease. However, there is limited local data on the prevalence of osteoporosis in end-stage renal disease.
Objective: The current study evaluated the epidemiology of osteoporosis in end-stage rental disease patients at a Saudi Arabian tertiary care center.
Methods: This cross-sectional retrospective study was conducted using data obtained between 1 January 2016 and 31 December 2019 at the Dialysis Center at King Abdulaziz Medical City, Riyadh, Saudi Arabia. End-stage rental disease patients who were aged ≥50 years and underwent hemodialysis for at least 1 year were included, while those with documented metabolic bone disease and absence of bone mineral density data were excluded.
Results: Sixty-four end-stage rental disease patients undergoing hemodialysis met the inclusion criteria. The patients underwent bone mineral density measurement at the discretion of the treating physician. The mean patients' age was 73 ± 11.5 years and 76% were women. The overall prevalence of osteoporosis was 37.5%, and it was similarly distributed among women and men (38.8% and 33.3%, respectively). Nine of the 15 male patients (60%) and 24 of the 49 female patients (49%) had fractures. Twenty-five (39%) patients used glucocorticoids. Osteoporosis was most commonly identified in the femoral neck (26.2%), followed by proximal femur (19.4%), and lumbar spine (18.8%). A high rate of osteoporosis was significantly associated with older age and being underweight.
Conclusion: A high rate of low bone mineral density was demonstrated in end-stage renal disease patients. The femoral neck was the most common osteoporosis site in this patient population, and advanced age and underweight were possible risk factors for low bone mass. |
| first_indexed | 2024-04-11T08:49:16Z |
| format | Article |
| id | doaj.art-097f7571f214421b91e528af30d6ea82 |
| institution | Directory Open Access Journal |
| issn | 1658-631X |
| language | English |
| last_indexed | 2024-04-11T08:49:16Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Medicine and Medical Sciences |
| spelling | doaj.art-097f7571f214421b91e528af30d6ea822022-12-22T04:33:42ZengWolters Kluwer Medknow PublicationsSaudi Journal of Medicine and Medical Sciences1658-631X2022-01-0110325926510.4103/sjmms.sjmms_639_21Prevalence and risk factors of osteoporosis in Saudi end-stage renal disease patients on hemodialysisMoeber M MahzariAhmed R AlibrahimNawaf A AlghamdiMuatassem A AlsadhanSaad M AlmoamaryEmad M MasuadiAwad S Al ShahraniBackground: Osteoporosis is characterized by a decrease in bone mineral density, thereby increasing the risk of pathological fractures. It is a common complication of chronic kidney disease. However, there is limited local data on the prevalence of osteoporosis in end-stage renal disease. Objective: The current study evaluated the epidemiology of osteoporosis in end-stage rental disease patients at a Saudi Arabian tertiary care center. Methods: This cross-sectional retrospective study was conducted using data obtained between 1 January 2016 and 31 December 2019 at the Dialysis Center at King Abdulaziz Medical City, Riyadh, Saudi Arabia. End-stage rental disease patients who were aged ≥50 years and underwent hemodialysis for at least 1 year were included, while those with documented metabolic bone disease and absence of bone mineral density data were excluded. Results: Sixty-four end-stage rental disease patients undergoing hemodialysis met the inclusion criteria. The patients underwent bone mineral density measurement at the discretion of the treating physician. The mean patients' age was 73 ± 11.5 years and 76% were women. The overall prevalence of osteoporosis was 37.5%, and it was similarly distributed among women and men (38.8% and 33.3%, respectively). Nine of the 15 male patients (60%) and 24 of the 49 female patients (49%) had fractures. Twenty-five (39%) patients used glucocorticoids. Osteoporosis was most commonly identified in the femoral neck (26.2%), followed by proximal femur (19.4%), and lumbar spine (18.8%). A high rate of osteoporosis was significantly associated with older age and being underweight. Conclusion: A high rate of low bone mineral density was demonstrated in end-stage renal disease patients. The femoral neck was the most common osteoporosis site in this patient population, and advanced age and underweight were possible risk factors for low bone mass.http://www.sjmms.net/article.asp?issn=1658-631X;year=2022;volume=10;issue=3;spage=259;epage=265;aulast=Mahzaribone mineral densityend-stage renal diseaseosteopeniaosteoporosisprevalencesaudi arabia |
| spellingShingle | Moeber M Mahzari Ahmed R Alibrahim Nawaf A Alghamdi Muatassem A Alsadhan Saad M Almoamary Emad M Masuadi Awad S Al Shahrani Prevalence and risk factors of osteoporosis in Saudi end-stage renal disease patients on hemodialysis Saudi Journal of Medicine and Medical Sciences bone mineral density end-stage renal disease osteopenia osteoporosis prevalence saudi arabia |
| title | Prevalence and risk factors of osteoporosis in Saudi end-stage renal disease patients on hemodialysis |
| title_full | Prevalence and risk factors of osteoporosis in Saudi end-stage renal disease patients on hemodialysis |
| title_fullStr | Prevalence and risk factors of osteoporosis in Saudi end-stage renal disease patients on hemodialysis |
| title_full_unstemmed | Prevalence and risk factors of osteoporosis in Saudi end-stage renal disease patients on hemodialysis |
| title_short | Prevalence and risk factors of osteoporosis in Saudi end-stage renal disease patients on hemodialysis |
| title_sort | prevalence and risk factors of osteoporosis in saudi end stage renal disease patients on hemodialysis |
| topic | bone mineral density end-stage renal disease osteopenia osteoporosis prevalence saudi arabia |
| url | http://www.sjmms.net/article.asp?issn=1658-631X;year=2022;volume=10;issue=3;spage=259;epage=265;aulast=Mahzari |
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