Roles of JNK/Nrf2 Pathway on Hemin-Induced Heme Oxygenase-1 Activation in MCF-7 Human Breast Cancer Cells

Roles of JNK/Nrf2 Pathway on Hemin-Induced Heme Oxygenase-1 Activation in MCF-7 Human Breast Cancer Cells

Heme oxygenase-1 (HO-1) is highly induced in various human disease states, including cancer, indicating that HO-1 is an emerging target of cancer therapy. In this study, we investigated that the mechanisms of hemin-induced HO-1 expression and its signaling pathways in human breast cancer cell. We us...

Full description

Bibliographic Details
Main Authors: Hye-Yeon Jang, On-Yu Hong, Eun-Yong Chung, Kwang-Hyun Park, Jong-Suk Kim
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Medicina
Subjects:
heme oxygenase-1
JNK
Nrf2
breast cancer
MCF-7
hemin
Online Access:https://www.mdpi.com/1010-660X/56/6/268

Similar Items

Similar Items