Suppressing miRNA-15a/-16 expression by interleukin-6 enhances drug-resistance in myeloma cells

Suppressing miRNA-15a/-16 expression by interleukin-6 enhances drug-resistance in myeloma cells

<p>Abstract</p> <p>The bone marrow microenvironment facilitates the survival, differentiation, and proliferation of myeloma (MM) cells. This study identified that microRNA-15a and -16 expressions tightly correlated with proliferation and drug sensitivity of MM cells. miRNA-15a/-16...

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Bibliographic Details
Main Authors: Chang Hong, Xu Yan, Zou Dehui, Yu Zhen, Sui Weiwei, Zhang Li, An Gang, Hao Mu, Qiu Lugui
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/4/1/37

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