Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive–Compulsive Disorder

Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive–Compulsive Disorder

Selective serotonin reuptake inhibitors (SSRIs) are the only effective pharmacological treatments for obsessive–compulsive disorder (OCD). Nonetheless, their generally limited efficacy, side-effects, and delayed onset of action require improved medications for this highly prevalent disorder. Preclin...

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Bibliographic Details
Main Authors: Michelle M. Rodriguez, Carl Overshiner, J. David Leander, Xia Li, Denise Morrow, Richard G. Conway, David L. Nelson, Karin Briner, Jeffrey M. Witkin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Psychiatry
Subjects:
obsessive–compulsive disorder
5-HT2C receptors
schedule-induced polydipsia
marble-burying
fluoxetine
Ro 60-0175
Online Access:http://journal.frontiersin.org/article/10.3389/fpsyt.2017.00089/full

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