| Summary: | <i>Actinotignum schaalii</i> is an anaerobic, gram-positive commensal organism of the urogenital tract. <i>A. schaalii</i> typically causes urinary tract infections, predominantly in the elderly. Here, we describe the first case of <i>A. schaalii</i> infection presenting as cellulitis and abscess in a patient with common variable immunodeficiency. The patient was successfully treated with an incision and drainage and a prolonged antibiotic course. <i>A. schaalii</i> infection should be considered in sterile abscesses, and anaerobic cultures should be requested in the absence of positive routine cultures.
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