Staphylococcal Infections and Neonatal Skin: Data from Literature and Suggestions for the Clinical Management from Four Challenging Patients
Staphylococcal infections in neonates might be associated with skin blistering since early antibiotic therapy has been shown to limit infection spread and positively influence outcomes; therefore, neonatologists should be aware of these conditions. This review examines the recent literature on the m...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/12/4/632 |
| _version_ | 1797606682934640640 |
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| author | Domenico Umberto De Rose Flaminia Pugnaloni Ludovica Martini Iliana Bersani Maria Paola Ronchetti Andrea Diociaiuti May El Hachem Andrea Dotta Cinzia Auriti |
| author_facet | Domenico Umberto De Rose Flaminia Pugnaloni Ludovica Martini Iliana Bersani Maria Paola Ronchetti Andrea Diociaiuti May El Hachem Andrea Dotta Cinzia Auriti |
| author_sort | Domenico Umberto De Rose |
| collection | DOAJ |
| description | Staphylococcal infections in neonates might be associated with skin blistering since early antibiotic therapy has been shown to limit infection spread and positively influence outcomes; therefore, neonatologists should be aware of these conditions. This review examines the recent literature on the management of Staphylococcal infections that involve neonatal skin, discussing the most appropriate clinical approach to four cases of neonatal blistering diseases with Staphylococcal infections: a case of Staphylococcal bullous impetigo, a case of Staphylococcal scalded skin syndrome (SSSS), a case of epidermolysis bullosa with overlapping Staphylococcal infection, and a case of burns with overlapping Staphylococcal infection. In treating Staphylococcal infections involving skin in neonates, the presence or absence of systemic symptoms should be considered. In the lack of evidence-based guidelines in this age category, treatment should be individualized according to several factors including the extension of the disease or further skin comorbidities (such as skin fragility), with a multidisciplinary approach. |
| first_indexed | 2024-03-11T05:18:32Z |
| format | Article |
| id | doaj.art-098767c9465d4b2aae610a8d7c9e8118 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-11T05:18:32Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-098767c9465d4b2aae610a8d7c9e81182023-11-17T18:01:45ZengMDPI AGAntibiotics2079-63822023-03-0112463210.3390/antibiotics12040632Staphylococcal Infections and Neonatal Skin: Data from Literature and Suggestions for the Clinical Management from Four Challenging PatientsDomenico Umberto De Rose0Flaminia Pugnaloni1Ludovica Martini2Iliana Bersani3Maria Paola Ronchetti4Andrea Diociaiuti5May El Hachem6Andrea Dotta7Cinzia Auriti8Neonatal Intensive Care Unit, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, ItalyNeonatal Intensive Care Unit, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, ItalyNeonatal Intensive Care Unit, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, ItalyNeonatal Intensive Care Unit, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, ItalyNeonatal Intensive Care Unit, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, ItalyDermatology Unit and Genodermatosis Unit, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, ItalyDermatology Unit and Genodermatosis Unit, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, ItalyNeonatal Intensive Care Unit, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, ItalyNeonatal Intensive Care Unit, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, ItalyStaphylococcal infections in neonates might be associated with skin blistering since early antibiotic therapy has been shown to limit infection spread and positively influence outcomes; therefore, neonatologists should be aware of these conditions. This review examines the recent literature on the management of Staphylococcal infections that involve neonatal skin, discussing the most appropriate clinical approach to four cases of neonatal blistering diseases with Staphylococcal infections: a case of Staphylococcal bullous impetigo, a case of Staphylococcal scalded skin syndrome (SSSS), a case of epidermolysis bullosa with overlapping Staphylococcal infection, and a case of burns with overlapping Staphylococcal infection. In treating Staphylococcal infections involving skin in neonates, the presence or absence of systemic symptoms should be considered. In the lack of evidence-based guidelines in this age category, treatment should be individualized according to several factors including the extension of the disease or further skin comorbidities (such as skin fragility), with a multidisciplinary approach.https://www.mdpi.com/2079-6382/12/4/632bullous impetigoStaphylococcal scalded skin syndromeepidermolysis bullosaburns<i>Staphylococcus aureus</i> |
| spellingShingle | Domenico Umberto De Rose Flaminia Pugnaloni Ludovica Martini Iliana Bersani Maria Paola Ronchetti Andrea Diociaiuti May El Hachem Andrea Dotta Cinzia Auriti Staphylococcal Infections and Neonatal Skin: Data from Literature and Suggestions for the Clinical Management from Four Challenging Patients Antibiotics bullous impetigo Staphylococcal scalded skin syndrome epidermolysis bullosa burns <i>Staphylococcus aureus</i> |
| title | Staphylococcal Infections and Neonatal Skin: Data from Literature and Suggestions for the Clinical Management from Four Challenging Patients |
| title_full | Staphylococcal Infections and Neonatal Skin: Data from Literature and Suggestions for the Clinical Management from Four Challenging Patients |
| title_fullStr | Staphylococcal Infections and Neonatal Skin: Data from Literature and Suggestions for the Clinical Management from Four Challenging Patients |
| title_full_unstemmed | Staphylococcal Infections and Neonatal Skin: Data from Literature and Suggestions for the Clinical Management from Four Challenging Patients |
| title_short | Staphylococcal Infections and Neonatal Skin: Data from Literature and Suggestions for the Clinical Management from Four Challenging Patients |
| title_sort | staphylococcal infections and neonatal skin data from literature and suggestions for the clinical management from four challenging patients |
| topic | bullous impetigo Staphylococcal scalded skin syndrome epidermolysis bullosa burns <i>Staphylococcus aureus</i> |
| url | https://www.mdpi.com/2079-6382/12/4/632 |
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