Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury

Proteinuria is an adverse prognostic feature in renal diseases. In proteinuric nephropathies, filtered proteins exert an injurious effect on the renal tubulointerstitium, resulting in inflammation and fibrosis. In the present study, we assessed to what extent complement activation via the lectin pat...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Samy Alghadban, Hany I. Kenawy, Thomas Dudler, Wilhelm J. Schwaeble, Nigel J. Brunskill
التنسيق: مقال
اللغة:English
منشور في: Frontiers Media S.A. 2019-09-01
سلاسل:Frontiers in Immunology
الموضوعات:
الوصول للمادة أونلاين:https://www.frontiersin.org/article/10.3389/fimmu.2019.02238/full