STATINS AND THE RISK OF DIABETES MELLITUS

Randomized controlled trials have clearly demonstrated the efficacy of statins in reduction of serum low density lipoprotein cholesterol level by 25-50% from the baseline. Statins may increase the risk of diabetes mellitus (DM) in long-term therapy and use of high doses. Diabetogenic action is stati...

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Main Author: O. M. Drapkina
Format: Article
Language:English
Published: Столичная издательская компания 2015-09-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:http://www.rpcardio.ru/jour/article/view/111
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author O. M. Drapkina
author_facet O. M. Drapkina
author_sort O. M. Drapkina
collection DOAJ
description Randomized controlled trials have clearly demonstrated the efficacy of statins in reduction of serum low density lipoprotein cholesterol level by 25-50% from the baseline. Statins may increase the risk of diabetes mellitus (DM) in long-term therapy and use of high doses. Diabetogenic action is statins class effect and does not depend on their hydrophobic or hydrophilic properties. However, the use of statins in patients with DM is obligatory. The statins diabetogenic  risk is exaggerated and we will continue to treat our patients with statins.
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series Рациональная фармакотерапия в кардиологии
spelling doaj.art-098975c6564d4660a8ea5d922026e40a2023-09-02T03:42:58ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-019444444710.1234/1819-6446-2013-4-444-447110STATINS AND THE RISK OF DIABETES MELLITUSO. M. Drapkina0Первый Московский медицинский университет имени И.М. Сеченова, МоскваRandomized controlled trials have clearly demonstrated the efficacy of statins in reduction of serum low density lipoprotein cholesterol level by 25-50% from the baseline. Statins may increase the risk of diabetes mellitus (DM) in long-term therapy and use of high doses. Diabetogenic action is statins class effect and does not depend on their hydrophobic or hydrophilic properties. However, the use of statins in patients with DM is obligatory. The statins diabetogenic  risk is exaggerated and we will continue to treat our patients with statins.http://www.rpcardio.ru/jour/article/view/111статиныриск сахарного диабета
spellingShingle O. M. Drapkina
STATINS AND THE RISK OF DIABETES MELLITUS
Рациональная фармакотерапия в кардиологии
статины
риск сахарного диабета
title STATINS AND THE RISK OF DIABETES MELLITUS
title_full STATINS AND THE RISK OF DIABETES MELLITUS
title_fullStr STATINS AND THE RISK OF DIABETES MELLITUS
title_full_unstemmed STATINS AND THE RISK OF DIABETES MELLITUS
title_short STATINS AND THE RISK OF DIABETES MELLITUS
title_sort statins and the risk of diabetes mellitus
topic статины
риск сахарного диабета
url http://www.rpcardio.ru/jour/article/view/111
work_keys_str_mv AT omdrapkina statinsandtheriskofdiabetesmellitus