STATINS AND THE RISK OF DIABETES MELLITUS
Randomized controlled trials have clearly demonstrated the efficacy of statins in reduction of serum low density lipoprotein cholesterol level by 25-50% from the baseline. Statins may increase the risk of diabetes mellitus (DM) in long-term therapy and use of high doses. Diabetogenic action is stati...
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Format: | Article |
Language: | English |
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Столичная издательская компания
2015-09-01
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Series: | Рациональная фармакотерапия в кардиологии |
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Online Access: | http://www.rpcardio.ru/jour/article/view/111 |
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author | O. M. Drapkina |
author_facet | O. M. Drapkina |
author_sort | O. M. Drapkina |
collection | DOAJ |
description | Randomized controlled trials have clearly demonstrated the efficacy of statins in reduction of serum low density lipoprotein cholesterol level by 25-50% from the baseline. Statins may increase the risk of diabetes mellitus (DM) in long-term therapy and use of high doses. Diabetogenic action is statins class effect and does not depend on their hydrophobic or hydrophilic properties. However, the use of statins in patients with DM is obligatory. The statins diabetogenic risk is exaggerated and we will continue to treat our patients with statins. |
first_indexed | 2024-03-12T11:06:07Z |
format | Article |
id | doaj.art-098975c6564d4660a8ea5d922026e40a |
institution | Directory Open Access Journal |
issn | 1819-6446 2225-3653 |
language | English |
last_indexed | 2024-03-12T11:06:07Z |
publishDate | 2015-09-01 |
publisher | Столичная издательская компания |
record_format | Article |
series | Рациональная фармакотерапия в кардиологии |
spelling | doaj.art-098975c6564d4660a8ea5d922026e40a2023-09-02T03:42:58ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-019444444710.1234/1819-6446-2013-4-444-447110STATINS AND THE RISK OF DIABETES MELLITUSO. M. Drapkina0Первый Московский медицинский университет имени И.М. Сеченова, МоскваRandomized controlled trials have clearly demonstrated the efficacy of statins in reduction of serum low density lipoprotein cholesterol level by 25-50% from the baseline. Statins may increase the risk of diabetes mellitus (DM) in long-term therapy and use of high doses. Diabetogenic action is statins class effect and does not depend on their hydrophobic or hydrophilic properties. However, the use of statins in patients with DM is obligatory. The statins diabetogenic risk is exaggerated and we will continue to treat our patients with statins.http://www.rpcardio.ru/jour/article/view/111статиныриск сахарного диабета |
spellingShingle | O. M. Drapkina STATINS AND THE RISK OF DIABETES MELLITUS Рациональная фармакотерапия в кардиологии статины риск сахарного диабета |
title | STATINS AND THE RISK OF DIABETES MELLITUS |
title_full | STATINS AND THE RISK OF DIABETES MELLITUS |
title_fullStr | STATINS AND THE RISK OF DIABETES MELLITUS |
title_full_unstemmed | STATINS AND THE RISK OF DIABETES MELLITUS |
title_short | STATINS AND THE RISK OF DIABETES MELLITUS |
title_sort | statins and the risk of diabetes mellitus |
topic | статины риск сахарного диабета |
url | http://www.rpcardio.ru/jour/article/view/111 |
work_keys_str_mv | AT omdrapkina statinsandtheriskofdiabetesmellitus |