Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT study
ABSTRACTBackground Tuberculosis (TB) has a significant treatment burden for patients, requiring at least six months of anti-TB treatment (ATT) with multiple medicines. Ensuring good adherence to ATT is central to global TB strategies, including those in high-income, low-TB incidence (HILI) settings....
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Health Psychology and Behavioral Medicine |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21642850.2023.2277289 |
| _version_ | 1797449872647913472 |
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| author | Annie S. K. Jones Rob Horne Jacqui White Trish Costello Marcia Darvell Aaron S. Karat Karina Kielmann Helen R. Stagg Adam T. Hill Heinke Kunst Colin N. J. Campbell Marc C. I. Lipman |
| author_facet | Annie S. K. Jones Rob Horne Jacqui White Trish Costello Marcia Darvell Aaron S. Karat Karina Kielmann Helen R. Stagg Adam T. Hill Heinke Kunst Colin N. J. Campbell Marc C. I. Lipman |
| author_sort | Annie S. K. Jones |
| collection | DOAJ |
| description | ABSTRACTBackground Tuberculosis (TB) has a significant treatment burden for patients, requiring at least six months of anti-TB treatment (ATT) with multiple medicines. Ensuring good adherence to ATT is central to global TB strategies, including those in high-income, low-TB incidence (HILI) settings. For adherence interventions to be successful and deliverable, they need to address the personal and environmental factors influencing patient and provider behaviour.Purpose This paper describes the application of theory and research evidence to inform the design process of the IMPACT manualised intervention to support ATT adherence for adults with TB disease in the United Kingdom (UK). It also provides a full description of the resulting intervention.Methods We synthesised findings from our formative research (qualitative and quantitative scoping reviews and patient and carer interviews) and supplemented these with clinic observations, a literature review, and healthcare provider interviews. Findings were mapped to the guiding theoretical framework (Perceptions and Practicalities Approach) which was operationalised to design the intervention components and content. An Intervention Development Group (IDG) of relevant stakeholders were consulted to adapt the intervention to local clinical settings.Results The pragmatic, deliverable components and content for the IMPACT intervention included: (1) an enhanced, structured, risk assessment to systematically identify risk factors for non-adherence plus locally-adapted guidance to mitigate these; and (2) patient educational materials (an animated video and interactive patient booklet) about TB and its treatment, to communicate the need for treatment and address common concerns.Conclusions Using a theory– and evidence– based approach incorporating stakeholder input, we have developed a multi-component, pragmatic, manualised intervention, which addresses patients’ personal barriers to adherence within local service resources to improve adherence to ATT within UK TB services. |
| first_indexed | 2024-03-09T14:31:22Z |
| format | Article |
| id | doaj.art-098dedd71a2b46a08913715cf7954f98 |
| institution | Directory Open Access Journal |
| issn | 2164-2850 |
| language | English |
| last_indexed | 2024-03-09T14:31:22Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Health Psychology and Behavioral Medicine |
| spelling | doaj.art-098dedd71a2b46a08913715cf7954f982023-11-27T23:33:16ZengTaylor & Francis GroupHealth Psychology and Behavioral Medicine2164-28502024-12-0112110.1080/21642850.2023.2277289Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT studyAnnie S. K. Jones0Rob Horne1Jacqui White2Trish Costello3Marcia Darvell4Aaron S. Karat5Karina Kielmann6Helen R. Stagg7Adam T. Hill8Heinke Kunst9Colin N. J. Campbell10Marc C. I. Lipman11Centre for Behavioural Medicine, Research Department of Practice and Policy, University College London (UCL) School of Pharmacy, UCL, London, UKCentre for Behavioural Medicine, Research Department of Practice and Policy, University College London (UCL) School of Pharmacy, UCL, London, UKWhittington Health NHS Trust, The Whittington Hospital, London, UKUCL Respiratory, Division of Medicine, UCL, London, UKUCL Respiratory, Division of Medicine, UCL, London, UKInstitute for Global Health and Development, Queen Margaret University, Edinburgh, UKInstitute for Global Health and Development, Queen Margaret University, Edinburgh, UKUsher Institute, University of Edinburgh, Edinburgh, UKQueen’s Medical Research Institute, University of Edinburgh, Edinburgh, UKBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, LondonUCL Respiratory, Division of Medicine, UCL, London, UKUCL Respiratory, Division of Medicine, UCL, London, UKABSTRACTBackground Tuberculosis (TB) has a significant treatment burden for patients, requiring at least six months of anti-TB treatment (ATT) with multiple medicines. Ensuring good adherence to ATT is central to global TB strategies, including those in high-income, low-TB incidence (HILI) settings. For adherence interventions to be successful and deliverable, they need to address the personal and environmental factors influencing patient and provider behaviour.Purpose This paper describes the application of theory and research evidence to inform the design process of the IMPACT manualised intervention to support ATT adherence for adults with TB disease in the United Kingdom (UK). It also provides a full description of the resulting intervention.Methods We synthesised findings from our formative research (qualitative and quantitative scoping reviews and patient and carer interviews) and supplemented these with clinic observations, a literature review, and healthcare provider interviews. Findings were mapped to the guiding theoretical framework (Perceptions and Practicalities Approach) which was operationalised to design the intervention components and content. An Intervention Development Group (IDG) of relevant stakeholders were consulted to adapt the intervention to local clinical settings.Results The pragmatic, deliverable components and content for the IMPACT intervention included: (1) an enhanced, structured, risk assessment to systematically identify risk factors for non-adherence plus locally-adapted guidance to mitigate these; and (2) patient educational materials (an animated video and interactive patient booklet) about TB and its treatment, to communicate the need for treatment and address common concerns.Conclusions Using a theory– and evidence– based approach incorporating stakeholder input, we have developed a multi-component, pragmatic, manualised intervention, which addresses patients’ personal barriers to adherence within local service resources to improve adherence to ATT within UK TB services.https://www.tandfonline.com/doi/10.1080/21642850.2023.2277289Intervention developmenttuberculosistreatment adherence |
| spellingShingle | Annie S. K. Jones Rob Horne Jacqui White Trish Costello Marcia Darvell Aaron S. Karat Karina Kielmann Helen R. Stagg Adam T. Hill Heinke Kunst Colin N. J. Campbell Marc C. I. Lipman Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT study Health Psychology and Behavioral Medicine Intervention development tuberculosis treatment adherence |
| title | Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT study |
| title_full | Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT study |
| title_fullStr | Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT study |
| title_full_unstemmed | Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT study |
| title_short | Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT study |
| title_sort | development and description of a theory driven evidence based complex intervention to improve adherence to treatment for tuberculosis in the uk the impact study |
| topic | Intervention development tuberculosis treatment adherence |
| url | https://www.tandfonline.com/doi/10.1080/21642850.2023.2277289 |
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