Label-free detection of transport kinetics and inhibitor binding of membrane transport proteins with a two-mode plasmonic sensor

Membrane transporters translocate molecules across cell membranes and are involved in a variety of cellular processes. However, there is still no label-free technique for measuring the transport kinetics of non-charged species through membrane transporters. Here, we develop a new method based on sur...

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Bibliographic Details
Main Authors: Chia-Wei Kuo, Tse-Han Kuo, Hui-An Lee, Yu-Ting Lin, Cheng-Jung Kuo, Kai-Hung Hsiao, Meng-Hua Yang, Kevin Tanady, Shu-Yu Chang, Tzy-Rong Lin, Ling Chao
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Biosensors and Bioelectronics: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590137022000784

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