Double coronary thrombosis in a patient with Behçet's disease
Behçet's disease is a chronic relapsing multisystem autoinflammatory condition, in which cardiac involvement is rare, but among the most life-threatening complications. Treatment is largely empirical, and is aimed at suppressing vasculitis. In this role glucocorticoids and colchicine are freque...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-07-01
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| Series: | Revista Portuguesa de Cardiologia |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0870255120302687 |
| _version_ | 1818508294267863040 |
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| author | Luís Abreu Bruno Marmelo Júlio Gil Hugo Antunes Maria Luísa Gonçalves Pedro Ferreira Emanuel Correia Costa Cabral |
| author_facet | Luís Abreu Bruno Marmelo Júlio Gil Hugo Antunes Maria Luísa Gonçalves Pedro Ferreira Emanuel Correia Costa Cabral |
| author_sort | Luís Abreu |
| collection | DOAJ |
| description | Behçet's disease is a chronic relapsing multisystem autoinflammatory condition, in which cardiac involvement is rare, but among the most life-threatening complications. Treatment is largely empirical, and is aimed at suppressing vasculitis. In this role glucocorticoids and colchicine are frequently used.We present the case of a 42-year-old male with previously diagnosed Behçet's disease presenting to our emergency department with an anterior-inferior STEMI. He presented combined thrombosis of the distal anterior descending coronary artery and proximal right coronary artery, and was treated with sequential primary percutaneous coronary interventions and implantation of drug-eluting stents, but required two interventions due to high thrombotic load.His clinical course during hospitalization was good, with no systolic dysfunction at discharge. During follow-up, he has so far had no new cardiovascular events. Resumo: A doença de Behçet (BD) é uma doença autoimune crónica e recidivante, na qual o envolvimento cardíaco é muito raro, mas encontra-se entre as complicações fatais. O tratamento é em grande parte empírico e destina-se a suprimir a vasculite. Nesse papel, os glicocorticoides e a colchicina são frequentemente utilizados.Apresentamos o caso de um homem de 42 anos, com diagnóstico prévio de doença de Behçet que recorreu ao nosso serviço de emergência com STEMI anteroinferior. Apresentou trombose simultânea da artéria coronária descendente anterior distal e da artéria coronária direita proximal e foi tratada com intervenção coronária percutânea primária com stent revestido de drogas de forma sequencial, mas necessitando de duas intervenções devido à recorrência trombótica.Teve boa evolução clínica durante o internamento, não apresentando disfunção sistólica na alta. Durante o seguimento, até à data, não ocorreu novo evento cardiovascular. |
| first_indexed | 2024-12-10T22:29:38Z |
| format | Article |
| id | doaj.art-0993d1b39ed1490a92de0b47718984d4 |
| institution | Directory Open Access Journal |
| issn | 0870-2551 |
| language | English |
| last_indexed | 2024-12-10T22:29:38Z |
| publishDate | 2020-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Revista Portuguesa de Cardiologia |
| spelling | doaj.art-0993d1b39ed1490a92de0b47718984d42022-12-22T01:31:05ZengElsevierRevista Portuguesa de Cardiologia0870-25512020-07-01397407.e1407.e4Double coronary thrombosis in a patient with Behçet's diseaseLuís Abreu0Bruno Marmelo1Júlio Gil2Hugo Antunes3Maria Luísa Gonçalves4Pedro Ferreira5Emanuel Correia6Costa Cabral7Corresponding author.; Serviço Cardiologia, Centro Hospitalar Tondela Viseu, Viseu, PortugalServiço Cardiologia, Centro Hospitalar Tondela Viseu, Viseu, PortugalServiço Cardiologia, Centro Hospitalar Tondela Viseu, Viseu, PortugalServiço Cardiologia, Centro Hospitalar Tondela Viseu, Viseu, PortugalServiço Cardiologia, Centro Hospitalar Tondela Viseu, Viseu, PortugalServiço Cardiologia, Centro Hospitalar Tondela Viseu, Viseu, PortugalServiço Cardiologia, Centro Hospitalar Tondela Viseu, Viseu, PortugalServiço Cardiologia, Centro Hospitalar Tondela Viseu, Viseu, PortugalBehçet's disease is a chronic relapsing multisystem autoinflammatory condition, in which cardiac involvement is rare, but among the most life-threatening complications. Treatment is largely empirical, and is aimed at suppressing vasculitis. In this role glucocorticoids and colchicine are frequently used.We present the case of a 42-year-old male with previously diagnosed Behçet's disease presenting to our emergency department with an anterior-inferior STEMI. He presented combined thrombosis of the distal anterior descending coronary artery and proximal right coronary artery, and was treated with sequential primary percutaneous coronary interventions and implantation of drug-eluting stents, but required two interventions due to high thrombotic load.His clinical course during hospitalization was good, with no systolic dysfunction at discharge. During follow-up, he has so far had no new cardiovascular events. Resumo: A doença de Behçet (BD) é uma doença autoimune crónica e recidivante, na qual o envolvimento cardíaco é muito raro, mas encontra-se entre as complicações fatais. O tratamento é em grande parte empírico e destina-se a suprimir a vasculite. Nesse papel, os glicocorticoides e a colchicina são frequentemente utilizados.Apresentamos o caso de um homem de 42 anos, com diagnóstico prévio de doença de Behçet que recorreu ao nosso serviço de emergência com STEMI anteroinferior. Apresentou trombose simultânea da artéria coronária descendente anterior distal e da artéria coronária direita proximal e foi tratada com intervenção coronária percutânea primária com stent revestido de drogas de forma sequencial, mas necessitando de duas intervenções devido à recorrência trombótica.Teve boa evolução clínica durante o internamento, não apresentando disfunção sistólica na alta. Durante o seguimento, até à data, não ocorreu novo evento cardiovascular.http://www.sciencedirect.com/science/article/pii/S0870255120302687Doença de BehçetSíndrome coronária agudaIntervenção coronária percutânea primária |
| spellingShingle | Luís Abreu Bruno Marmelo Júlio Gil Hugo Antunes Maria Luísa Gonçalves Pedro Ferreira Emanuel Correia Costa Cabral Double coronary thrombosis in a patient with Behçet's disease Revista Portuguesa de Cardiologia Doença de Behçet Síndrome coronária aguda Intervenção coronária percutânea primária |
| title | Double coronary thrombosis in a patient with Behçet's disease |
| title_full | Double coronary thrombosis in a patient with Behçet's disease |
| title_fullStr | Double coronary thrombosis in a patient with Behçet's disease |
| title_full_unstemmed | Double coronary thrombosis in a patient with Behçet's disease |
| title_short | Double coronary thrombosis in a patient with Behçet's disease |
| title_sort | double coronary thrombosis in a patient with behcet s disease |
| topic | Doença de Behçet Síndrome coronária aguda Intervenção coronária percutânea primária |
| url | http://www.sciencedirect.com/science/article/pii/S0870255120302687 |
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