One-site versus two-site phacotrabeculectomy: a prospective randomized study
Marilita M Moschos,1 Irini P Chatziralli,2 Michael Tsatsos3 1First Department of Ophthalmology, University of Athens, 2Second Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece; 3Department of Ophthalmology, Cambridge University Hospital NHS, Cambridge, UK Purpose: The purpose of...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2015-08-01
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| Series: | Clinical Interventions in Aging |
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| Online Access: | https://www.dovepress.com/one-site-versus-two-site-phacotrabeculectomy-anbspprospective-randomiz-peer-reviewed-article-CIA |
| _version_ | 1819129827944300544 |
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| author | Moschos MM Chatziralli IP Tsatsos M |
| author_facet | Moschos MM Chatziralli IP Tsatsos M |
| author_sort | Moschos MM |
| collection | DOAJ |
| description | Marilita M Moschos,1 Irini P Chatziralli,2 Michael Tsatsos3 1First Department of Ophthalmology, University of Athens, 2Second Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece; 3Department of Ophthalmology, Cambridge University Hospital NHS, Cambridge, UK Purpose: The purpose of this study is to compare the efficacy and safety of one-site and two-site combined phacotrabeculectomy with foldable posterior chamber intraocular lens implantation.Methods: Thirty-four patients (41 eyes) with glaucoma and cataract were randomly assigned to undergo either a one-site (22 eyes) or a two-site (19 eyes) combined procedure. One-site approach consisted of a standard superior phacotrabeculectomy with a limbus-based conjunctival flap, while two-site approach consisted of a clear cornea phacoemulsification and a separate superior trabeculectomy with a limbus-based conjunctival flap.Results: Mean follow-up period was 54 months (standard deviation [SD] 2.3). Mean preoperative intraocular pressure (IOP) in the one-site group was 21.3 mmHg (SD 2.8) and in the two-site group was 21.8 mmHg (SD 3.0) (P>0.1). Mean postoperative IOP significantly decreased in both groups compared to the preoperative level and was 15.6 mmHg (SD 3.5) in the one-site group and 14.9 mmHg (SD 2.7) in the two-site group. Three months later, the difference between the two groups was not statistically significant (P=0.058). The one-site group required significantly more medications than the two-site group (P=0.03). Best-corrected visual acuity (BCVA) improved similarly in both groups, but there was less postoperative (induced) astigmatism in the two-site group in a marginal statistical level (P=0.058). Intra- and postoperative complications were comparable in the two groups.Conclusion: Both techniques yielded similar results concerning final BCVA and IOP reduction. However, the two-site group had less induced astigmatism and a better postoperative IOP control with less required postoperative antiglaucoma medications compared to the one-site group. Keywords: glaucoma, filtering surgery, intraocular pressure |
| first_indexed | 2024-12-22T08:49:55Z |
| format | Article |
| id | doaj.art-0996db7ff438488fb9ae2684d3ac0a91 |
| institution | Directory Open Access Journal |
| issn | 1178-1998 |
| language | English |
| last_indexed | 2024-12-22T08:49:55Z |
| publishDate | 2015-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Interventions in Aging |
| spelling | doaj.art-0996db7ff438488fb9ae2684d3ac0a912022-12-21T18:32:00ZengDove Medical PressClinical Interventions in Aging1178-19982015-08-01Volume 101393139923293One-site versus two-site phacotrabeculectomy: a prospective randomized studyMoschos MMChatziralli IPTsatsos MMarilita M Moschos,1 Irini P Chatziralli,2 Michael Tsatsos3 1First Department of Ophthalmology, University of Athens, 2Second Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece; 3Department of Ophthalmology, Cambridge University Hospital NHS, Cambridge, UK Purpose: The purpose of this study is to compare the efficacy and safety of one-site and two-site combined phacotrabeculectomy with foldable posterior chamber intraocular lens implantation.Methods: Thirty-four patients (41 eyes) with glaucoma and cataract were randomly assigned to undergo either a one-site (22 eyes) or a two-site (19 eyes) combined procedure. One-site approach consisted of a standard superior phacotrabeculectomy with a limbus-based conjunctival flap, while two-site approach consisted of a clear cornea phacoemulsification and a separate superior trabeculectomy with a limbus-based conjunctival flap.Results: Mean follow-up period was 54 months (standard deviation [SD] 2.3). Mean preoperative intraocular pressure (IOP) in the one-site group was 21.3 mmHg (SD 2.8) and in the two-site group was 21.8 mmHg (SD 3.0) (P>0.1). Mean postoperative IOP significantly decreased in both groups compared to the preoperative level and was 15.6 mmHg (SD 3.5) in the one-site group and 14.9 mmHg (SD 2.7) in the two-site group. Three months later, the difference between the two groups was not statistically significant (P=0.058). The one-site group required significantly more medications than the two-site group (P=0.03). Best-corrected visual acuity (BCVA) improved similarly in both groups, but there was less postoperative (induced) astigmatism in the two-site group in a marginal statistical level (P=0.058). Intra- and postoperative complications were comparable in the two groups.Conclusion: Both techniques yielded similar results concerning final BCVA and IOP reduction. However, the two-site group had less induced astigmatism and a better postoperative IOP control with less required postoperative antiglaucoma medications compared to the one-site group. Keywords: glaucoma, filtering surgery, intraocular pressurehttps://www.dovepress.com/one-site-versus-two-site-phacotrabeculectomy-anbspprospective-randomiz-peer-reviewed-article-CIAglaucomaphacotrabeculectomyintraocular pressure |
| spellingShingle | Moschos MM Chatziralli IP Tsatsos M One-site versus two-site phacotrabeculectomy: a prospective randomized study Clinical Interventions in Aging glaucoma phacotrabeculectomy intraocular pressure |
| title | One-site versus two-site phacotrabeculectomy: a prospective randomized study |
| title_full | One-site versus two-site phacotrabeculectomy: a prospective randomized study |
| title_fullStr | One-site versus two-site phacotrabeculectomy: a prospective randomized study |
| title_full_unstemmed | One-site versus two-site phacotrabeculectomy: a prospective randomized study |
| title_short | One-site versus two-site phacotrabeculectomy: a prospective randomized study |
| title_sort | one site versus two site phacotrabeculectomy a nbsp prospective randomized study |
| topic | glaucoma phacotrabeculectomy intraocular pressure |
| url | https://www.dovepress.com/one-site-versus-two-site-phacotrabeculectomy-anbspprospective-randomiz-peer-reviewed-article-CIA |
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