Research Progress on the Mechanism of the Acupuncture Regulating Neuro-Endocrine-Immune Network System
As one of the conventional treatment methods, acupuncture is an indispensable component of Traditional Chinese Medicine. Currently, acupuncture has been partly accepted throughout the world, but the mechanism of acupuncture is still unclear. Since the theory of the neuro-endocrine-immune network was...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/8/8/149 |
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| author | Jingwen Cui Wanrong Song Yipeng Jin Huihao Xu Kai Fan Degui Lin Zhihui Hao Jiahao Lin |
| author_facet | Jingwen Cui Wanrong Song Yipeng Jin Huihao Xu Kai Fan Degui Lin Zhihui Hao Jiahao Lin |
| author_sort | Jingwen Cui |
| collection | DOAJ |
| description | As one of the conventional treatment methods, acupuncture is an indispensable component of Traditional Chinese Medicine. Currently, acupuncture has been partly accepted throughout the world, but the mechanism of acupuncture is still unclear. Since the theory of the neuro-endocrine-immune network was put forward, new insights have been brought into the understanding of the mechanism of acupuncture. Studies have proven that acupuncture is a mechanical stimulus that can activate local cell functions and neuroreceptors. It also regulates the release of related biomolecules (peptide hormones, lipid hormones, neuromodulators and neurotransmitters, and other small and large biomolecules) in the microenvironment, where they can affect each other and further activate the neuroendocrine-immune network to achieve holistic regulation. Recently, growing efforts have been made in the research on the mechanism of acupuncture. Some researchers have transitioned from studying the mechanism of acupuncture as a single linear pathway to using systems approaches, including metabolomics, genomics, proteomics and biological pathway analysis. This review summarizes the research progress on the neuro-endocrine-immune network related mechanism of acupuncture and discusses its current challenges and future directions. |
| first_indexed | 2024-03-10T08:18:12Z |
| format | Article |
| id | doaj.art-099bab1b7c8742dc9424fef482722c16 |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-10T08:18:12Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-099bab1b7c8742dc9424fef482722c162023-11-22T10:08:35ZengMDPI AGVeterinary Sciences2306-73812021-07-018814910.3390/vetsci8080149Research Progress on the Mechanism of the Acupuncture Regulating Neuro-Endocrine-Immune Network SystemJingwen Cui0Wanrong Song1Yipeng Jin2Huihao Xu3Kai Fan4Degui Lin5Zhihui Hao6Jiahao Lin7College of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, ChinaAs one of the conventional treatment methods, acupuncture is an indispensable component of Traditional Chinese Medicine. Currently, acupuncture has been partly accepted throughout the world, but the mechanism of acupuncture is still unclear. Since the theory of the neuro-endocrine-immune network was put forward, new insights have been brought into the understanding of the mechanism of acupuncture. Studies have proven that acupuncture is a mechanical stimulus that can activate local cell functions and neuroreceptors. It also regulates the release of related biomolecules (peptide hormones, lipid hormones, neuromodulators and neurotransmitters, and other small and large biomolecules) in the microenvironment, where they can affect each other and further activate the neuroendocrine-immune network to achieve holistic regulation. Recently, growing efforts have been made in the research on the mechanism of acupuncture. Some researchers have transitioned from studying the mechanism of acupuncture as a single linear pathway to using systems approaches, including metabolomics, genomics, proteomics and biological pathway analysis. This review summarizes the research progress on the neuro-endocrine-immune network related mechanism of acupuncture and discusses its current challenges and future directions.https://www.mdpi.com/2306-7381/8/8/149acupunctureneuro-endocrine-immune networkmechanismbidirectional regulationmicroenvironment |
| spellingShingle | Jingwen Cui Wanrong Song Yipeng Jin Huihao Xu Kai Fan Degui Lin Zhihui Hao Jiahao Lin Research Progress on the Mechanism of the Acupuncture Regulating Neuro-Endocrine-Immune Network System Veterinary Sciences acupuncture neuro-endocrine-immune network mechanism bidirectional regulation microenvironment |
| title | Research Progress on the Mechanism of the Acupuncture Regulating Neuro-Endocrine-Immune Network System |
| title_full | Research Progress on the Mechanism of the Acupuncture Regulating Neuro-Endocrine-Immune Network System |
| title_fullStr | Research Progress on the Mechanism of the Acupuncture Regulating Neuro-Endocrine-Immune Network System |
| title_full_unstemmed | Research Progress on the Mechanism of the Acupuncture Regulating Neuro-Endocrine-Immune Network System |
| title_short | Research Progress on the Mechanism of the Acupuncture Regulating Neuro-Endocrine-Immune Network System |
| title_sort | research progress on the mechanism of the acupuncture regulating neuro endocrine immune network system |
| topic | acupuncture neuro-endocrine-immune network mechanism bidirectional regulation microenvironment |
| url | https://www.mdpi.com/2306-7381/8/8/149 |
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