Antibiotic sensitivity pattern of Staphylococcus aureus from clinical isolates in a tertiary health institution in Kano, Northwestern Nigeria
BACKGROUND: The importance of Staphylococcus aureus as a persistent nosocomial and community acquired pathogen has become a global health concern. It has a remarkable capability of evolving different mechanisms of resistance to most antimicrobial agents. The aim of the present study is to establish...
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| Format: | Article |
| Language: | English |
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The Pan African Medical Journal
2011-01-01
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| Series: | The Pan African Medical Journal |
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| Online Access: | http://www.panafrican-med-journal.com/content/article/8/4/pdf/4.pdf |
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| author | Nwankwo Emmanuel Onwubiko Nasiru Magaji Sadiq |
| author_facet | Nwankwo Emmanuel Onwubiko Nasiru Magaji Sadiq |
| author_sort | Nwankwo Emmanuel Onwubiko |
| collection | DOAJ |
| description | BACKGROUND: The importance of Staphylococcus aureus as a persistent nosocomial and community acquired pathogen has become a global health concern. It has a remarkable capability of evolving different mechanisms of resistance to most antimicrobial agents. The aim of the present study is to establish the incidence of S. aureus in clinical specimens and its antibiotic sensitivity pattern to various antibiotics in this locality. METHODS: One hundred and fifty consecutive isolates of S. aureus obtained from various clinical specimens between January and December 2009 sent to the Medical Microbiology Laboratory Department of Aminu Kano Teaching Hospital (AKTH) were confirmed by standard bacteriological procedures. Antibiotic sensitivity pattern was carried out by disc diffusion method. RESULTS: The age group with the highest number of isolates was (0-10)yrs while wound infection had the highest frequency of S. aureus isolates (30.7%) in the study. Males (62.0%) were more infected than females (38.0%). The sensitivity pattern of S. aureus to the following antibiotics; Gentamicin, Amoxycillin/clavulanate, Streptomycin, Cloxacillin, Erythromycin, Chloramphenicol, Cotrimoxazole, Tetracycline, Penicillin, Ciprofloxacin, Ofloxacin, Levofloxacin, Ceftriaxone, Amoxycillin and vancomycin were 92.4%, 63.0%, 44.2%, 35.8%, 52.4%, 61.9%, 15.5%, 31.2%, 7.1%, 78.9%, 76.6%, 100%, 71.4%, 30.7% and 100% respectively. Methicillin resistant isolates were sensitive to Levofloxacin 93.7% and Ofloxacin 68.7%. CONCLUSION: The results of the present study show that the fluoroquinolones are effective in the management of Staphylococcus aureus infections including methicillin resistant strains in this environment. |
| first_indexed | 2024-12-19T21:46:30Z |
| format | Article |
| id | doaj.art-099bb6a1eea54166a7cd15f8ae5cc97f |
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| issn | 1937-8688 |
| language | English |
| last_indexed | 2024-12-19T21:46:30Z |
| publishDate | 2011-01-01 |
| publisher | The Pan African Medical Journal |
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| series | The Pan African Medical Journal |
| spelling | doaj.art-099bb6a1eea54166a7cd15f8ae5cc97f2022-12-21T20:04:31ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86882011-01-0184Antibiotic sensitivity pattern of Staphylococcus aureus from clinical isolates in a tertiary health institution in Kano, Northwestern NigeriaNwankwo Emmanuel OnwubikoNasiru Magaji SadiqBACKGROUND: The importance of Staphylococcus aureus as a persistent nosocomial and community acquired pathogen has become a global health concern. It has a remarkable capability of evolving different mechanisms of resistance to most antimicrobial agents. The aim of the present study is to establish the incidence of S. aureus in clinical specimens and its antibiotic sensitivity pattern to various antibiotics in this locality. METHODS: One hundred and fifty consecutive isolates of S. aureus obtained from various clinical specimens between January and December 2009 sent to the Medical Microbiology Laboratory Department of Aminu Kano Teaching Hospital (AKTH) were confirmed by standard bacteriological procedures. Antibiotic sensitivity pattern was carried out by disc diffusion method. RESULTS: The age group with the highest number of isolates was (0-10)yrs while wound infection had the highest frequency of S. aureus isolates (30.7%) in the study. Males (62.0%) were more infected than females (38.0%). The sensitivity pattern of S. aureus to the following antibiotics; Gentamicin, Amoxycillin/clavulanate, Streptomycin, Cloxacillin, Erythromycin, Chloramphenicol, Cotrimoxazole, Tetracycline, Penicillin, Ciprofloxacin, Ofloxacin, Levofloxacin, Ceftriaxone, Amoxycillin and vancomycin were 92.4%, 63.0%, 44.2%, 35.8%, 52.4%, 61.9%, 15.5%, 31.2%, 7.1%, 78.9%, 76.6%, 100%, 71.4%, 30.7% and 100% respectively. Methicillin resistant isolates were sensitive to Levofloxacin 93.7% and Ofloxacin 68.7%. CONCLUSION: The results of the present study show that the fluoroquinolones are effective in the management of Staphylococcus aureus infections including methicillin resistant strains in this environment.http://www.panafrican-med-journal.com/content/article/8/4/pdf/4.pdf Staphylococcus aureusantibiotic sensitivityNigeriaKano |
| spellingShingle | Nwankwo Emmanuel Onwubiko Nasiru Magaji Sadiq Antibiotic sensitivity pattern of Staphylococcus aureus from clinical isolates in a tertiary health institution in Kano, Northwestern Nigeria The Pan African Medical Journal Staphylococcus aureus antibiotic sensitivity Nigeria Kano |
| title | Antibiotic sensitivity pattern of Staphylococcus aureus from clinical isolates in a tertiary health institution in Kano, Northwestern Nigeria |
| title_full | Antibiotic sensitivity pattern of Staphylococcus aureus from clinical isolates in a tertiary health institution in Kano, Northwestern Nigeria |
| title_fullStr | Antibiotic sensitivity pattern of Staphylococcus aureus from clinical isolates in a tertiary health institution in Kano, Northwestern Nigeria |
| title_full_unstemmed | Antibiotic sensitivity pattern of Staphylococcus aureus from clinical isolates in a tertiary health institution in Kano, Northwestern Nigeria |
| title_short | Antibiotic sensitivity pattern of Staphylococcus aureus from clinical isolates in a tertiary health institution in Kano, Northwestern Nigeria |
| title_sort | antibiotic sensitivity pattern of staphylococcus aureus from clinical isolates in a tertiary health institution in kano northwestern nigeria |
| topic | Staphylococcus aureus antibiotic sensitivity Nigeria Kano |
| url | http://www.panafrican-med-journal.com/content/article/8/4/pdf/4.pdf |
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