Molecular Pathogenesis of Gene Regulation by the <i>miR-150</i> Duplex: <i>miR-150-3p</i> Regulates <i>TNS4</i> in Lung Adenocarcinoma
Based on our miRNA expression signatures, we focused on <i>miR-150-5p</i> (the guide strand) and <i>miR-150-3p</i> (the passenger strand) to investigate their functional significance in lung adenocarcinoma (LUAD). Downregulation of <i>miR-150</i> duplex was confir...
Main Authors: | Shunsuke Misono, Naohiko Seki, Keiko Mizuno, Yasutaka Yamada, Akifumi Uchida, Hiroki Sanada, Shogo Moriya, Naoko Kikkawa, Tomohiro Kumamoto, Takayuki Suetsugu, Hiromasa Inoue |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-04-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/5/601 |
Similar Items
-
Regulation of Oncogenic Targets by Tumor-Suppressive <i>miR-150-3p</i> in Lung Squamous Cell Carcinoma
by: Keiko Mizuno, et al.
Published: (2021-12-01) -
Involvement of Dual Strands of <i>miR-143</i> (<i>miR-143-5p</i> and <i>miR-143-3p</i>) and Their Target Oncogenes in the Molecular Pathogenesis of Lung Adenocarcinoma
by: Hiroki Sanada, et al.
Published: (2019-09-01) -
Impact of <i>miR-1</i>/<i>miR-133</i> Clustered miRNAs: <i>PFN2</i> Facilitates Malignant Phenotypes in Head and Neck Squamous Cell Carcinoma
by: Shunichi Asai, et al.
Published: (2022-03-01) -
<i>FAM64A</i>: A Novel Oncogenic Target of Lung Adenocarcinoma Regulated by Both Strands of <i>miR-99a</i> (<i>miR-99a-5p</i> and <i>miR-99a-3p</i>)
by: Keiko Mizuno, et al.
Published: (2020-09-01) -
Enhanced expression of miR-21 and miR-150 is a feature of anti-mitochondrial antibody-negative primary biliary cholangitis
by: Urszula Wasik, et al.
Published: (2020-01-01)