Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with Covid-19
Covid-19 is a global challenge that drives health care to its limits. Biological parameters associated with increased risk of severe or fatal disease courses were identified, including conditions connected with a poor state of health, organ damage, and coagulation dysfunction. In a recent study, ris...
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| Format: | Article |
| Language: | English |
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University of Technology, Baghdad
2022-06-01
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| Series: | Journal of Applied Sciences and Nanotechnology |
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| Online Access: | https://jasn.uotechnology.edu.iq/article_17847_856be1484d2bd8c9b2e4197c748f0b86.pdf |
| _version_ | 1811343732900888576 |
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| author | Rafah Salih Ali Taha Nadira Mohamed |
| author_facet | Rafah Salih Ali Taha Nadira Mohamed |
| author_sort | Rafah Salih |
| collection | DOAJ |
| description | Covid-19 is a global challenge that drives health care to its limits. Biological parameters associated with increased risk of severe or fatal disease courses were identified, including conditions connected with a poor state of health, organ damage, and coagulation dysfunction. In a recent study, risk factors like age, sex, blood group (ABO), smoking, and several biomarkers like white blood cells, lymphocytes, C-reactive protein (CRP), ferritin, D-dimer, and potassium level were considered. One hundred nasopharyngeal swabs and blood samples were collected from Iraqi patients and classified according to the severity of the disease into five groups: Asymptomatic, Mild, Moderate, Severe, and Deceased, according to the recommendations of the World Health Organization (WHO). The current study was based on the risk factors and their effect on disease severity (age, sex, blood type, and smoking). As a result, there was a substantial positive linear link (R2=0.91) between getting older and increasing disease severity. Study results were showed a little statistically significant difference in the number of males and females infected with SARS-CoV-2. Interestingly, males were shown to be more susceptible to infection than females. Also, because type (O) blood is more extensively distributed in the Middle East population than the other blood types, those with type (O) blood are more susceptible to infection. Because smokers and non-smokers were distributed at random across different disease severity levels, there was no statistically significant link between smoking status and COVID-19 severity. All parameters (plasma protein and liver enzymes) showed statistically significant differences, especially between the deceased groups except K level, which did not differ significantly in all groups. This study aimed to investigate some biological markers during infection to see if there was a link between these measurements and risk factors, as well as the severity and progression of the disease. |
| first_indexed | 2024-04-13T19:35:08Z |
| format | Article |
| id | doaj.art-09a1079d9cd348e89558c6762f950404 |
| institution | Directory Open Access Journal |
| issn | 2788-6867 |
| language | English |
| last_indexed | 2024-04-13T19:35:08Z |
| publishDate | 2022-06-01 |
| publisher | University of Technology, Baghdad |
| record_format | Article |
| series | Journal of Applied Sciences and Nanotechnology |
| spelling | doaj.art-09a1079d9cd348e89558c6762f9504042022-12-22T02:33:03ZengUniversity of Technology, BaghdadJournal of Applied Sciences and Nanotechnology2788-68672022-06-012211212310.53293/jasn.2021.4112.107117847Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with Covid-19Rafah Salih0Ali Taha1Nadira Mohamed2Central Public Health Laboratory, Ministry of Health – IraqBiotechnology Division, Department of Applied Sciences, University of Technology – IraqPharmacy College /Al-Nahrain University – IraqCovid-19 is a global challenge that drives health care to its limits. Biological parameters associated with increased risk of severe or fatal disease courses were identified, including conditions connected with a poor state of health, organ damage, and coagulation dysfunction. In a recent study, risk factors like age, sex, blood group (ABO), smoking, and several biomarkers like white blood cells, lymphocytes, C-reactive protein (CRP), ferritin, D-dimer, and potassium level were considered. One hundred nasopharyngeal swabs and blood samples were collected from Iraqi patients and classified according to the severity of the disease into five groups: Asymptomatic, Mild, Moderate, Severe, and Deceased, according to the recommendations of the World Health Organization (WHO). The current study was based on the risk factors and their effect on disease severity (age, sex, blood type, and smoking). As a result, there was a substantial positive linear link (R2=0.91) between getting older and increasing disease severity. Study results were showed a little statistically significant difference in the number of males and females infected with SARS-CoV-2. Interestingly, males were shown to be more susceptible to infection than females. Also, because type (O) blood is more extensively distributed in the Middle East population than the other blood types, those with type (O) blood are more susceptible to infection. Because smokers and non-smokers were distributed at random across different disease severity levels, there was no statistically significant link between smoking status and COVID-19 severity. All parameters (plasma protein and liver enzymes) showed statistically significant differences, especially between the deceased groups except K level, which did not differ significantly in all groups. This study aimed to investigate some biological markers during infection to see if there was a link between these measurements and risk factors, as well as the severity and progression of the disease.https://jasn.uotechnology.edu.iq/article_17847_856be1484d2bd8c9b2e4197c748f0b86.pdfbiological parameterssmokingwhite blood cellsserum proteinscovid-19 |
| spellingShingle | Rafah Salih Ali Taha Nadira Mohamed Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with Covid-19 Journal of Applied Sciences and Nanotechnology biological parameters smoking white blood cells serum proteins covid-19 |
| title | Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with Covid-19 |
| title_full | Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with Covid-19 |
| title_fullStr | Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with Covid-19 |
| title_full_unstemmed | Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with Covid-19 |
| title_short | Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with Covid-19 |
| title_sort | determination of risk factors and some biomarkers parameters during infected iraqis with covid 19 |
| topic | biological parameters smoking white blood cells serum proteins covid-19 |
| url | https://jasn.uotechnology.edu.iq/article_17847_856be1484d2bd8c9b2e4197c748f0b86.pdf |
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