Mechanistic study on the side arm effect in a palladium/Xu-Phos-catalyzed enantioselective alkoxyalkenylation of γ-hydroxyalkenes

Abstract Recently, the asymmetric bifunctionalization of alkenes has received much attention. However, the development of enantioselective alkoxyalkenylation has posed a considerable challenge and has lagged largely behind. Herein, we report a new palladium-catalyzed enantioselective alkoxyalkenylat...

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Bibliographic Details
Main Authors: Shuai Zhu, Zihao Ye, Ming-Jie Chen, Lei Wang, Yu-Zhuo Wang, Ke-Nan Zhang, Wen-Bo Li, Han-Ming Ding, Zhiming Li, Junliang Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43202-5

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