Novel insight into the underlying dysregulation mechanisms of immune cell-to-cell communication by analyzing multitissue single-cell atlas of two COVID-19 patients

Novel insight into the underlying dysregulation mechanisms of immune cell-to-cell communication by analyzing multitissue single-cell atlas of two COVID-19 patients

Abstract How does SARS-CoV-2 cause lung microenvironment disturbance and inflammatory storm is still obscure. We here performed the single-cell transcriptome sequencing from lung, blood, and bone marrow of two dead COVID-19 patients and detected the cellular communication among them. Our results dem...

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Bibliographic Details
Main Authors: Shijie Qin, Xiaohong Yao, Weiwei Li, Canbiao Wang, Weijun Xu, Zhenhua Gan, Yang Yang, Aifang Zhong, Bin Wang, Zhicheng He, Jian Wu, Qiuyue Wu, Weijun Jiang, Ying Han, Fan Wang, Zhihua Wang, Yuehua Ke, Jun Zhao, Junyin Gao, Liang Qu, Ping Jin, Miao Guan, Xinyi Xia, Xiuwu Bian
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05814-z

Internet

https://doi.org/10.1038/s41419-023-05814-z

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