Akt Phosphorylation and Neuronal Survival after Traumatic Brain Injury in Mice

Akt Phosphorylation and Neuronal Survival after Traumatic Brain Injury in Mice

The serine-threonine kinase, Akt, is involved in the survival signaling pathways in many cell systems. The present study examined phosphorylation of Akt at serine-473 and DNA fragmentation after traumatic brain injury (TBI) in mice. Immunohistochemistry showed phospho-Akt was decreased in the injure...

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Bibliographic Details
Main Authors:	Nobuo Noshita, Anders Lewén, Taku Sugawara, Pak H. Chan
Format:	Article
Language:	English
Published:	Elsevier 2002-04-01
Series:	Neurobiology of Disease
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996102904821

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