Regional drinking water composition effects on hip fracture risk: a spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
Abstract Geographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Disc...
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| Format: | Article |
| Language: | English |
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Universidade de São Paulo
2020-10-01
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| Series: | Saúde e Sociedade |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-12902020000200206&tlng=en |
| _version_ | 1819005950532517888 |
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| author | Carla Maria Oliveira Hugo Teixeira Sandra Maria Alves Maria Fátima Pina |
| author_facet | Carla Maria Oliveira Hugo Teixeira Sandra Maria Alves Maria Fátima Pina |
| author_sort | Carla Maria Oliveira |
| collection | DOAJ |
| description | Abstract Geographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Discharge Register we selected admissions of patients aged ≥50 years, diagnosed with HF caused by low/moderate energy traumas. Water components and characteristics were selected at the municipality level. A spatial generalized additive model with a negative binomial distribution as a link function was used to estimate the association of HF with variations in DWC. There were 96,905HF (77.3% in women). The spatial pattern of HF risk was attenuated after being adjusted for water parameters. Results show an indirect association between calcium, magnesium, and iron and HF risk but no clear relation between aluminum, cadmium, fluoride, manganese, or color and HF risk. Regarding pH, the 6.7pH and 7pH interval seems to pose a lower risk. Different dose-response relationships were identified. The increase of calcium, magnesium, and iron values in DWC seems to reduce regional HF risk. Long-term exposure to water parameters, even within the regulatory limits, might increase the regional HF risk. |
| first_indexed | 2024-12-21T00:00:56Z |
| format | Article |
| id | doaj.art-09a8462d70cc4c9bbc18dc68bebea499 |
| institution | Directory Open Access Journal |
| issn | 1984-0470 |
| language | English |
| last_indexed | 2024-12-21T00:00:56Z |
| publishDate | 2020-10-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Saúde e Sociedade |
| spelling | doaj.art-09a8462d70cc4c9bbc18dc68bebea4992022-12-21T19:22:36ZengUniversidade de São PauloSaúde e Sociedade1984-04702020-10-0129210.1590/s0104-12902020200094Regional drinking water composition effects on hip fracture risk: a spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010Carla Maria Oliveirahttps://orcid.org/0000-0002-4594-1723Hugo Teixeirahttps://orcid.org/0000-0001-8283-5826Sandra Maria Alveshttps://orcid.org/0000-0002-2318-7491Maria Fátima Pinahttps://orcid.org/0000-0002-1521-7865Abstract Geographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Discharge Register we selected admissions of patients aged ≥50 years, diagnosed with HF caused by low/moderate energy traumas. Water components and characteristics were selected at the municipality level. A spatial generalized additive model with a negative binomial distribution as a link function was used to estimate the association of HF with variations in DWC. There were 96,905HF (77.3% in women). The spatial pattern of HF risk was attenuated after being adjusted for water parameters. Results show an indirect association between calcium, magnesium, and iron and HF risk but no clear relation between aluminum, cadmium, fluoride, manganese, or color and HF risk. Regarding pH, the 6.7pH and 7pH interval seems to pose a lower risk. Different dose-response relationships were identified. The increase of calcium, magnesium, and iron values in DWC seems to reduce regional HF risk. Long-term exposure to water parameters, even within the regulatory limits, might increase the regional HF risk.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-12902020000200206&tlng=enHip FractureDrinking Water CompositionHospital AdmissionsSpatial Epidemiology |
| spellingShingle | Carla Maria Oliveira Hugo Teixeira Sandra Maria Alves Maria Fátima Pina Regional drinking water composition effects on hip fracture risk: a spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 Saúde e Sociedade Hip Fracture Drinking Water Composition Hospital Admissions Spatial Epidemiology |
| title | Regional drinking water composition effects on hip fracture risk: a spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
| title_full | Regional drinking water composition effects on hip fracture risk: a spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
| title_fullStr | Regional drinking water composition effects on hip fracture risk: a spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
| title_full_unstemmed | Regional drinking water composition effects on hip fracture risk: a spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
| title_short | Regional drinking water composition effects on hip fracture risk: a spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
| title_sort | regional drinking water composition effects on hip fracture risk a spatial analysis of nationwide hospital admissions in portugal from 2000 to 2010 |
| topic | Hip Fracture Drinking Water Composition Hospital Admissions Spatial Epidemiology |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-12902020000200206&tlng=en |
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