Acute Confusional State in a Neuropsychiatric Systemic Lupus Erythematosus Patient: A Case Report

Systemic Lupus Erythematosus (SLE) affects various systems in human including central and peripheral nervous systems. The Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) is a severe complication of SLE which causes a formidable challenge in term of diagnosis and its management. Acute confusion...

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Main Authors: Sambhu Prasad, Shikha Jha
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2022-05-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://www.jcdr.net/articles/PDF/16334/52527_CE[Ra1]_F(KR)_PF1(SC_SHU)_PFA(NC_KM)_PN(KM).pdf
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author Sambhu Prasad
Shikha Jha
author_facet Sambhu Prasad
Shikha Jha
author_sort Sambhu Prasad
collection DOAJ
description Systemic Lupus Erythematosus (SLE) affects various systems in human including central and peripheral nervous systems. The Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) is a severe complication of SLE which causes a formidable challenge in term of diagnosis and its management. Acute confusional state (delirium) is a rare entity of numerous symptoms of NPSLE which is being overlooked even though it is associated with increased mortality. The present case report describe about the presentation of SLE consisting of hyperpigmentation maculopapular rashes over face, neck regions, lower back and extremities in a 36-year-old female with abrupt onset and fluctuating course of psychotic symptoms, acute confusional state and oddities in behaviours. Treatment with low dose of antipsychotic (aripiprazole) resolve the symptom with due consideration taken to rule out steroid induced manifestation of above symptoms.
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spelling doaj.art-09a8e7e60bd74fe592a01dd979b792112023-02-13T08:26:08ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-05-01165VD03VD0510.7860/JCDR/2022/52527.16334Acute Confusional State in a Neuropsychiatric Systemic Lupus Erythematosus Patient: A Case ReportSambhu Prasad0Shikha Jha1Assistant Professor, Department of Psychiatry, All India Institute of Medical Sciences, Patna, Bihar, India.Senior Resident, Department of Psychiatry, All India Institute of Medical Sciences, Patna, Bihar, India.Systemic Lupus Erythematosus (SLE) affects various systems in human including central and peripheral nervous systems. The Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) is a severe complication of SLE which causes a formidable challenge in term of diagnosis and its management. Acute confusional state (delirium) is a rare entity of numerous symptoms of NPSLE which is being overlooked even though it is associated with increased mortality. The present case report describe about the presentation of SLE consisting of hyperpigmentation maculopapular rashes over face, neck regions, lower back and extremities in a 36-year-old female with abrupt onset and fluctuating course of psychotic symptoms, acute confusional state and oddities in behaviours. Treatment with low dose of antipsychotic (aripiprazole) resolve the symptom with due consideration taken to rule out steroid induced manifestation of above symptoms.https://www.jcdr.net/articles/PDF/16334/52527_CE[Ra1]_F(KR)_PF1(SC_SHU)_PFA(NC_KM)_PN(KM).pdfantipsychotic treatmentdiagnostic challengefluctuating thinking and behaviour odditieshyperpigmented maculopapular rashes
spellingShingle Sambhu Prasad
Shikha Jha
Acute Confusional State in a Neuropsychiatric Systemic Lupus Erythematosus Patient: A Case Report
Journal of Clinical and Diagnostic Research
antipsychotic treatment
diagnostic challenge
fluctuating thinking and behaviour oddities
hyperpigmented maculopapular rashes
title Acute Confusional State in a Neuropsychiatric Systemic Lupus Erythematosus Patient: A Case Report
title_full Acute Confusional State in a Neuropsychiatric Systemic Lupus Erythematosus Patient: A Case Report
title_fullStr Acute Confusional State in a Neuropsychiatric Systemic Lupus Erythematosus Patient: A Case Report
title_full_unstemmed Acute Confusional State in a Neuropsychiatric Systemic Lupus Erythematosus Patient: A Case Report
title_short Acute Confusional State in a Neuropsychiatric Systemic Lupus Erythematosus Patient: A Case Report
title_sort acute confusional state in a neuropsychiatric systemic lupus erythematosus patient a case report
topic antipsychotic treatment
diagnostic challenge
fluctuating thinking and behaviour oddities
hyperpigmented maculopapular rashes
url https://www.jcdr.net/articles/PDF/16334/52527_CE[Ra1]_F(KR)_PF1(SC_SHU)_PFA(NC_KM)_PN(KM).pdf
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