Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers

We report the case of a 9-months-old boy that has presented a steroid-dependent post-pneumococcal chronic aseptic meningitis was associated with persistence of pneumococcal cell wall components in cerebrospinal fluid during more than 20 months. Suggesting that this antigenic persistence could be inv...

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Main Authors: Manon Ladeveze, Yann Dumont, G. Boursier, Frederic Batteux, Perrine Mahe, Aurelie Bensimon Borrull, Guillaume Sarrabay, Karine Bollore, Edouard Tuaillon, Sylvain Godreuil, Eric Jeziorski
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.762457/full
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author Manon Ladeveze
Yann Dumont
G. Boursier
Frederic Batteux
Perrine Mahe
Aurelie Bensimon Borrull
Guillaume Sarrabay
Karine Bollore
Karine Bollore
Edouard Tuaillon
Edouard Tuaillon
Edouard Tuaillon
Sylvain Godreuil
Sylvain Godreuil
Eric Jeziorski
Eric Jeziorski
author_facet Manon Ladeveze
Yann Dumont
G. Boursier
Frederic Batteux
Perrine Mahe
Aurelie Bensimon Borrull
Guillaume Sarrabay
Karine Bollore
Karine Bollore
Edouard Tuaillon
Edouard Tuaillon
Edouard Tuaillon
Sylvain Godreuil
Sylvain Godreuil
Eric Jeziorski
Eric Jeziorski
author_sort Manon Ladeveze
collection DOAJ
description We report the case of a 9-months-old boy that has presented a steroid-dependent post-pneumococcal chronic aseptic meningitis was associated with persistence of pneumococcal cell wall components in cerebrospinal fluid during more than 20 months. Suggesting that this antigenic persistence could be involved in post-infectious manifestations through innate immunity response.
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spelling doaj.art-09aa09593eb8477c9a5110b83cad30112022-12-21T21:49:49ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-02-011010.3389/fped.2022.762457762457Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory EmbersManon Ladeveze0Yann Dumont1G. Boursier2Frederic Batteux3Perrine Mahe4Aurelie Bensimon Borrull5Guillaume Sarrabay6Karine Bollore7Karine Bollore8Edouard Tuaillon9Edouard Tuaillon10Edouard Tuaillon11Sylvain Godreuil12Sylvain Godreuil13Eric Jeziorski14Eric Jeziorski15Département Urgences Post-Urgences, CEREMAIA, CHU de Montpellier, Montpellier, FranceLaboratoire de Bactériologie, CHU de Montpellier, Montpellier, FranceLaboratoire de Génétique des Maladies Rares et Autoinflammatoires, Département de Génétique Médicale, Maladies Rares et Médecine Personnalisée, CEREMAIA, CHU de Montpellier, Univ Montpellier, Montpellier, FrancePlateforme d'ImmunoMonitoring Vaccinal (PIMV), Laboratoire d'Immunologie, Hôpital Cochin, Paris, FranceDépartement Urgences Post-Urgences, CEREMAIA, CHU de Montpellier, Montpellier, FrancePlateforme d'ImmunoMonitoring Vaccinal (PIMV), Laboratoire d'Immunologie, Hôpital Cochin, Paris, FranceLaboratoire de Génétique des Maladies Rares et Autoinflammatoires, Département de Génétique Médicale, Maladies Rares et Médecine Personnalisée, CEREMAIA, CHU de Montpellier, Univ Montpellier, Montpellier, FrancePlateforme Exploration de cellules rares en immunologie et infectiologie, CHU de Montpellier, Montpellier, FrancePCCEI, INSERM, Univ Montpellier, Montpellier, FrancePlateforme Exploration de cellules rares en immunologie et infectiologie, CHU de Montpellier, Montpellier, FrancePCCEI, INSERM, Univ Montpellier, Montpellier, FranceLaboratoire de virologie, CHU de Montpellier, Montpellier, FranceLaboratoire de Bactériologie, CHU de Montpellier, Montpellier, FranceUMR IRD224-CNRS5290-UM MIVEGEC, Univ Montpellier, Montpellier, FranceDépartement Urgences Post-Urgences, CEREMAIA, CHU de Montpellier, Montpellier, FrancePCCEI, INSERM, Univ Montpellier, Montpellier, FranceWe report the case of a 9-months-old boy that has presented a steroid-dependent post-pneumococcal chronic aseptic meningitis was associated with persistence of pneumococcal cell wall components in cerebrospinal fluid during more than 20 months. Suggesting that this antigenic persistence could be involved in post-infectious manifestations through innate immunity response.https://www.frontiersin.org/articles/10.3389/fped.2022.762457/fullpneumococcal meningitispneumococcal cell wall componentsaseptic meningitischronic aseptic meningitisinnate immunity
spellingShingle Manon Ladeveze
Yann Dumont
G. Boursier
Frederic Batteux
Perrine Mahe
Aurelie Bensimon Borrull
Guillaume Sarrabay
Karine Bollore
Karine Bollore
Edouard Tuaillon
Edouard Tuaillon
Edouard Tuaillon
Sylvain Godreuil
Sylvain Godreuil
Eric Jeziorski
Eric Jeziorski
Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers
Frontiers in Pediatrics
pneumococcal meningitis
pneumococcal cell wall components
aseptic meningitis
chronic aseptic meningitis
innate immunity
title Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers
title_full Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers
title_fullStr Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers
title_full_unstemmed Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers
title_short Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers
title_sort case report persistency pneumococcal polysaccharide in cerebrospinal fluid during a post pneumococcal chronic aseptic meningitis coincidental or auto inflammatory embers
topic pneumococcal meningitis
pneumococcal cell wall components
aseptic meningitis
chronic aseptic meningitis
innate immunity
url https://www.frontiersin.org/articles/10.3389/fped.2022.762457/full
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