Changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspects
Purpose: The aim of this study was to evaluate the effects of pharmacologic mydriasis and Peripheral Iridotomy (PI) on ocular biometry and anterior chamber parameters in primary angle closure suspects. Methods: In this prospective interventional case series, 21 primary angle closure suspects were en...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016-07-01
|
| Series: | Journal of Optometry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1888429616000030 |
| _version_ | 1818457627903918080 |
|---|---|
| author | Mohammad Reza Razeghinejad Hamid Lashkarizadeh Mohammad Hossein Nowroozzadeh Mohammad Yazdanmehr |
| author_facet | Mohammad Reza Razeghinejad Hamid Lashkarizadeh Mohammad Hossein Nowroozzadeh Mohammad Yazdanmehr |
| author_sort | Mohammad Reza Razeghinejad |
| collection | DOAJ |
| description | Purpose: The aim of this study was to evaluate the effects of pharmacologic mydriasis and Peripheral Iridotomy (PI) on ocular biometry and anterior chamber parameters in primary angle closure suspects.
Methods: In this prospective interventional case series, 21 primary angle closure suspects were enrolled. Intraocular pressure, refraction, ocular biometry (Lenstar, LS900), and anterior chamber parameters (Pentacam HR) were measured at four occasions: before PI (before and after mydriasis with phenylephrine) and two weeks after PI (before and after mydriasis). The study was conducted on both eyes and only one eye per patient, in random, was included in the analysis.
Results: The mean age of the participants was 60 ± 7 years and 17 (81%) were female. There were no significant differences in intraocular pressure, refraction, keratometry, biometric and anterior chamber parameters between groups, except for anterior chamber volume, which showed increments with PI and mydriasis. The corresponding values for anterior chamber volume were as follows: 88.2 ± 13.7 mm3 before PI, undilated; 106.3 ± 18.8 before PI, dilated; 99.0 ± 14.6 after PI, undilated, and 107.4 ± 16.5 after PI, dilated (P < 0.001).
Conclusions: This study showed no change in the ocular biometric and anterior chamber parameters including iridocorneal angle after PI and/or pharmacologic mydriasis except for increments in anterior chamber volume. This factor has the potential to be used as a numerical proxy for iris position in evaluating and monitoring patients with primary angle closure suspects after PI. |
| first_indexed | 2024-12-14T22:45:35Z |
| format | Article |
| id | doaj.art-09aac28842c74f72a957b7e3b918ec54 |
| institution | Directory Open Access Journal |
| issn | 1888-4296 |
| language | English |
| last_indexed | 2024-12-14T22:45:35Z |
| publishDate | 2016-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Optometry |
| spelling | doaj.art-09aac28842c74f72a957b7e3b918ec542022-12-21T22:44:51ZengElsevierJournal of Optometry1888-42962016-07-019318919510.1016/j.optom.2016.01.001Changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspectsMohammad Reza Razeghinejad0Hamid Lashkarizadeh1Mohammad Hossein Nowroozzadeh2Mohammad Yazdanmehr3Poostchi Eye Research Centre, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranPoostchi Eye Research Centre, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranPoostchi Eye Research Centre, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranPoostchi Eye Research Centre, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranPurpose: The aim of this study was to evaluate the effects of pharmacologic mydriasis and Peripheral Iridotomy (PI) on ocular biometry and anterior chamber parameters in primary angle closure suspects. Methods: In this prospective interventional case series, 21 primary angle closure suspects were enrolled. Intraocular pressure, refraction, ocular biometry (Lenstar, LS900), and anterior chamber parameters (Pentacam HR) were measured at four occasions: before PI (before and after mydriasis with phenylephrine) and two weeks after PI (before and after mydriasis). The study was conducted on both eyes and only one eye per patient, in random, was included in the analysis. Results: The mean age of the participants was 60 ± 7 years and 17 (81%) were female. There were no significant differences in intraocular pressure, refraction, keratometry, biometric and anterior chamber parameters between groups, except for anterior chamber volume, which showed increments with PI and mydriasis. The corresponding values for anterior chamber volume were as follows: 88.2 ± 13.7 mm3 before PI, undilated; 106.3 ± 18.8 before PI, dilated; 99.0 ± 14.6 after PI, undilated, and 107.4 ± 16.5 after PI, dilated (P < 0.001). Conclusions: This study showed no change in the ocular biometric and anterior chamber parameters including iridocorneal angle after PI and/or pharmacologic mydriasis except for increments in anterior chamber volume. This factor has the potential to be used as a numerical proxy for iris position in evaluating and monitoring patients with primary angle closure suspects after PI.http://www.sciencedirect.com/science/article/pii/S1888429616000030Anterior chamber volumePeripheral iridotomyMydriasisNarrow angleOcular biometry |
| spellingShingle | Mohammad Reza Razeghinejad Hamid Lashkarizadeh Mohammad Hossein Nowroozzadeh Mohammad Yazdanmehr Changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspects Journal of Optometry Anterior chamber volume Peripheral iridotomy Mydriasis Narrow angle Ocular biometry |
| title | Changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspects |
| title_full | Changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspects |
| title_fullStr | Changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspects |
| title_full_unstemmed | Changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspects |
| title_short | Changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspects |
| title_sort | changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspects |
| topic | Anterior chamber volume Peripheral iridotomy Mydriasis Narrow angle Ocular biometry |
| url | http://www.sciencedirect.com/science/article/pii/S1888429616000030 |
| work_keys_str_mv | AT mohammadrezarazeghinejad changesinocularbiometryandanteriorchamberparametersafterpharmacologicmydriasisandperipheraliridotomyinprimaryangleclosuresuspects AT hamidlashkarizadeh changesinocularbiometryandanteriorchamberparametersafterpharmacologicmydriasisandperipheraliridotomyinprimaryangleclosuresuspects AT mohammadhosseinnowroozzadeh changesinocularbiometryandanteriorchamberparametersafterpharmacologicmydriasisandperipheraliridotomyinprimaryangleclosuresuspects AT mohammadyazdanmehr changesinocularbiometryandanteriorchamberparametersafterpharmacologicmydriasisandperipheraliridotomyinprimaryangleclosuresuspects |