The relationship between epicardial fat tissue thickness and red blood cell distribution width in patients with Type 2 diabetes mellitus
Aim: Red blood cell distribution width (RDW) and epicardial fat tissue (EFT) are considered as a novel risk factor for cardiovascular disease. However, their relationship in patients with type II diabetes mellitus (DM) has never investigated before. Materials and Methods: Our study was a single-cent...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2019-01-01
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| Series: | International Journal of the Cardiovascular Academy |
| Subjects: | |
| Online Access: | http://www.ijcva.com/article.asp?issn=2405-8181;year=2019;volume=5;issue=2;spage=47;epage=51;aulast=Yildiz |
| _version_ | 1797707433950314496 |
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| author | Abdulmelik Yildiz Cennet Yildiz Ahmet Karakurt |
| author_facet | Abdulmelik Yildiz Cennet Yildiz Ahmet Karakurt |
| author_sort | Abdulmelik Yildiz |
| collection | DOAJ |
| description | Aim: Red blood cell distribution width (RDW) and epicardial fat tissue (EFT) are considered as a novel risk factor for cardiovascular disease. However, their relationship in patients with type II diabetes mellitus (DM) has never investigated before. Materials and Methods: Our study was a single-center prospective study which included 159 diabetic patients and 153 healthy controls. Two-dimensional and M-mode echocardiographic examination was performed using standard apical, parasternal, and subcostal views in all the study participants. Results: EFT thickness and RDW were found to be significantly higher in diabetic patients compared to controls (4.3 ± 1.1 mm vs. 3.7 ± 1.0 mm P = 0.001 and 13.5 ± 0.7 vs. 13.2 ± 0.9 P = 0.044, respectively). EFT thickness and RDW were positively correlated. RDW value of 13.55 predicted EFT thickness >5 mm with a sensitivity of 61.7% and specificity of 58.8% (area under the curve [AUC]: 0.649 and P = 0.001). HgA1C value of >7 predicted EFT thickness ≥4.15 mm with a sensitivity of 60.7% and specificity of 60.4% (AUC: 0.651 and P < 0.001). No correlation found between RDW and HgA1C (AUC: 0.554 and P: 0.169). Conclusion: EFT thickness increased in diabetic patients, independent of age, gender, waist circumference, body mass index, and it was correlated with RDW and HgA1C. |
| first_indexed | 2024-03-12T06:07:20Z |
| format | Article |
| id | doaj.art-09ae5a1cd0664a7ca471057977200936 |
| institution | Directory Open Access Journal |
| issn | 2405-8181 2405-819X |
| language | English |
| last_indexed | 2024-03-12T06:07:20Z |
| publishDate | 2019-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | International Journal of the Cardiovascular Academy |
| spelling | doaj.art-09ae5a1cd0664a7ca4710579772009362023-09-03T03:29:09ZengGalenos Publishing HouseInternational Journal of the Cardiovascular Academy2405-81812405-819X2019-01-0152475110.4103/IJCA.IJCA_47_18The relationship between epicardial fat tissue thickness and red blood cell distribution width in patients with Type 2 diabetes mellitusAbdulmelik YildizCennet YildizAhmet KarakurtAim: Red blood cell distribution width (RDW) and epicardial fat tissue (EFT) are considered as a novel risk factor for cardiovascular disease. However, their relationship in patients with type II diabetes mellitus (DM) has never investigated before. Materials and Methods: Our study was a single-center prospective study which included 159 diabetic patients and 153 healthy controls. Two-dimensional and M-mode echocardiographic examination was performed using standard apical, parasternal, and subcostal views in all the study participants. Results: EFT thickness and RDW were found to be significantly higher in diabetic patients compared to controls (4.3 ± 1.1 mm vs. 3.7 ± 1.0 mm P = 0.001 and 13.5 ± 0.7 vs. 13.2 ± 0.9 P = 0.044, respectively). EFT thickness and RDW were positively correlated. RDW value of 13.55 predicted EFT thickness >5 mm with a sensitivity of 61.7% and specificity of 58.8% (area under the curve [AUC]: 0.649 and P = 0.001). HgA1C value of >7 predicted EFT thickness ≥4.15 mm with a sensitivity of 60.7% and specificity of 60.4% (AUC: 0.651 and P < 0.001). No correlation found between RDW and HgA1C (AUC: 0.554 and P: 0.169). Conclusion: EFT thickness increased in diabetic patients, independent of age, gender, waist circumference, body mass index, and it was correlated with RDW and HgA1C.http://www.ijcva.com/article.asp?issn=2405-8181;year=2019;volume=5;issue=2;spage=47;epage=51;aulast=YildizEpicardial fat tissue thicknessred blood cell distribution widthtype 2 diabetes mellitus |
| spellingShingle | Abdulmelik Yildiz Cennet Yildiz Ahmet Karakurt The relationship between epicardial fat tissue thickness and red blood cell distribution width in patients with Type 2 diabetes mellitus International Journal of the Cardiovascular Academy Epicardial fat tissue thickness red blood cell distribution width type 2 diabetes mellitus |
| title | The relationship between epicardial fat tissue thickness and red blood cell distribution width in patients with Type 2 diabetes mellitus |
| title_full | The relationship between epicardial fat tissue thickness and red blood cell distribution width in patients with Type 2 diabetes mellitus |
| title_fullStr | The relationship between epicardial fat tissue thickness and red blood cell distribution width in patients with Type 2 diabetes mellitus |
| title_full_unstemmed | The relationship between epicardial fat tissue thickness and red blood cell distribution width in patients with Type 2 diabetes mellitus |
| title_short | The relationship between epicardial fat tissue thickness and red blood cell distribution width in patients with Type 2 diabetes mellitus |
| title_sort | relationship between epicardial fat tissue thickness and red blood cell distribution width in patients with type 2 diabetes mellitus |
| topic | Epicardial fat tissue thickness red blood cell distribution width type 2 diabetes mellitus |
| url | http://www.ijcva.com/article.asp?issn=2405-8181;year=2019;volume=5;issue=2;spage=47;epage=51;aulast=Yildiz |
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