Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019)
Background and aimsDiabetes-related foot ulcers (DFU) are a persistent healthcare challenge, impacting both patients and healthcare systems, with adverse effects on quality of life and productivity. Our primary aim was to examine the trends in lifetime prevalence of DFU, as well as other micro- and...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-04-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1354385/full |
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| author | Hilde K. R. Riise Hilde K. R. Riise Jannicke Igland Jannicke Igland Marit Graue Anne Haugstvedt Truls Østbye Eirik Søfteland Eirik Søfteland Monica Hermann Sofia Carlsson Bjørn Olav Åsvold Bjørn Olav Åsvold Bjørn Olav Åsvold Marjolein M. Iversen |
| author_facet | Hilde K. R. Riise Hilde K. R. Riise Jannicke Igland Jannicke Igland Marit Graue Anne Haugstvedt Truls Østbye Eirik Søfteland Eirik Søfteland Monica Hermann Sofia Carlsson Bjørn Olav Åsvold Bjørn Olav Åsvold Bjørn Olav Åsvold Marjolein M. Iversen |
| author_sort | Hilde K. R. Riise |
| collection | DOAJ |
| description | Background and aimsDiabetes-related foot ulcers (DFU) are a persistent healthcare challenge, impacting both patients and healthcare systems, with adverse effects on quality of life and productivity. Our primary aim was to examine the trends in lifetime prevalence of DFU, as well as other micro- and macrovascular complications in the Trøndelag Health Study (HUNT) in Norway.MethodsThis study consists of individuals ≥20 years with diabetes participating in the population-based cross-sectional HUNT surveys (1995-2019). Prevalence ratios, comparing the lifetime prevalence of DFU and other relevant micro- and macrovascular complications between the HUNT surveys, were calculated using Poisson regression.ResultsThe lifetime prevalence (95% confidence interval (CI)) of a DFU requiring three or more weeks to heal was 11.0% (9.5-12.7) in HUNT2, 7.5% (6.3-8.8) in HUNT3 and 5.3% (4.4-6.3) in HUNT4. The decrease in DFU prevalence from 1995 to 2019 was observed in both men and women, for all age groups, and for both type 1 and type 2 diabetes. The highest lifetime prevalence of DFU was found among those with type 1 diabetes. The decrease in HbA1c from HUNT2 to HUNT4 did not differ between those with and without a DFU. The prevalence of chronic kidney disease (eGFR <60 mL/min/1.73 m2 (eGFR categories G3-G5)) increased in both individuals with and without a DFU.ConclusionResults from the HUNT surveys show a substantial decline in the lifetime prevalence of DFU from 1995 to 2019. |
| first_indexed | 2024-04-24T08:13:31Z |
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| id | doaj.art-09af2a261a8341569cc0daf5dd70a102 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-24T08:13:31Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Endocrinology |
| spelling | doaj.art-09af2a261a8341569cc0daf5dd70a1022024-04-17T04:45:39ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922024-04-011510.3389/fendo.2024.13543851354385Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019)Hilde K. R. Riise0Hilde K. R. Riise1Jannicke Igland2Jannicke Igland3Marit Graue4Anne Haugstvedt5Truls Østbye6Eirik Søfteland7Eirik Søfteland8Monica Hermann9Sofia Carlsson10Bjørn Olav Åsvold11Bjørn Olav Åsvold12Bjørn Olav Åsvold13Marjolein M. Iversen14Department of Medicine, Haukeland University Hospital, Bergen, NorwayDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, NorwayDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, NorwayDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, NorwayDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, NorwayDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, NorwayDepartment of Family Medicine and Community Health, Duke University School of Medicine, Durham, NC, United StatesDepartment of Medicine, Haukeland University Hospital, Bergen, NorwayDepartment of Clinical Medicine, University of Bergen, Bergen, NorwayDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, NorwayInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenHUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, NTNU – Norwegian University of Science and Technology, Trondheim, NorwayDepartment of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, NorwayHUNT Research Center, Department of Public Health and Nursing, NTNU – Norwegian University of Science and Technology, Levanger, NorwayDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, NorwayBackground and aimsDiabetes-related foot ulcers (DFU) are a persistent healthcare challenge, impacting both patients and healthcare systems, with adverse effects on quality of life and productivity. Our primary aim was to examine the trends in lifetime prevalence of DFU, as well as other micro- and macrovascular complications in the Trøndelag Health Study (HUNT) in Norway.MethodsThis study consists of individuals ≥20 years with diabetes participating in the population-based cross-sectional HUNT surveys (1995-2019). Prevalence ratios, comparing the lifetime prevalence of DFU and other relevant micro- and macrovascular complications between the HUNT surveys, were calculated using Poisson regression.ResultsThe lifetime prevalence (95% confidence interval (CI)) of a DFU requiring three or more weeks to heal was 11.0% (9.5-12.7) in HUNT2, 7.5% (6.3-8.8) in HUNT3 and 5.3% (4.4-6.3) in HUNT4. The decrease in DFU prevalence from 1995 to 2019 was observed in both men and women, for all age groups, and for both type 1 and type 2 diabetes. The highest lifetime prevalence of DFU was found among those with type 1 diabetes. The decrease in HbA1c from HUNT2 to HUNT4 did not differ between those with and without a DFU. The prevalence of chronic kidney disease (eGFR <60 mL/min/1.73 m2 (eGFR categories G3-G5)) increased in both individuals with and without a DFU.ConclusionResults from the HUNT surveys show a substantial decline in the lifetime prevalence of DFU from 1995 to 2019.https://www.frontiersin.org/articles/10.3389/fendo.2024.1354385/fulltype 2 diabetesdiabetes-related foot ulcerdiabetes complicationslifetime prevalenceprevalence |
| spellingShingle | Hilde K. R. Riise Hilde K. R. Riise Jannicke Igland Jannicke Igland Marit Graue Anne Haugstvedt Truls Østbye Eirik Søfteland Eirik Søfteland Monica Hermann Sofia Carlsson Bjørn Olav Åsvold Bjørn Olav Åsvold Bjørn Olav Åsvold Marjolein M. Iversen Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019) Frontiers in Endocrinology type 2 diabetes diabetes-related foot ulcer diabetes complications lifetime prevalence prevalence |
| title | Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019) |
| title_full | Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019) |
| title_fullStr | Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019) |
| title_full_unstemmed | Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019) |
| title_short | Decreasing lifetime prevalence of diabetes-related foot ulcers in Norway: repeated cross-sectional population-based surveys from the HUNT study (1995-2019) |
| title_sort | decreasing lifetime prevalence of diabetes related foot ulcers in norway repeated cross sectional population based surveys from the hunt study 1995 2019 |
| topic | type 2 diabetes diabetes-related foot ulcer diabetes complications lifetime prevalence prevalence |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2024.1354385/full |
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