Twenty Years of Equine Piroplasmosis Research: Global Distribution, Molecular Diagnosis, and Phylogeny
Equine piroplasmosis (EP), caused by the hemoparasites <i>Theileria equi</i>, <i>Theileria haneyi</i>, and <i>Babesia caballi</i>, is an important tick-borne disease of equines that is prevalent in most parts of the world. Infection may affect animal welfare and h...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-11-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/9/11/926 |
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| author | Sharon Tirosh-Levy Yuval Gottlieb Lindsay M. Fry Donald P. Knowles Amir Steinman |
| author_facet | Sharon Tirosh-Levy Yuval Gottlieb Lindsay M. Fry Donald P. Knowles Amir Steinman |
| author_sort | Sharon Tirosh-Levy |
| collection | DOAJ |
| description | Equine piroplasmosis (EP), caused by the hemoparasites <i>Theileria equi</i>, <i>Theileria haneyi</i>, and <i>Babesia caballi</i>, is an important tick-borne disease of equines that is prevalent in most parts of the world. Infection may affect animal welfare and has economic impacts related to limitations in horse transport between endemic and non-endemic regions, reduced performance of sport horses and treatment costs. Here, we analyzed the epidemiological, serological, and molecular diagnostic data published in the last 20 years, and all DNA sequences submitted to GenBank database, to describe the current global prevalence of these parasites. We demonstrate that EP is endemic in most parts of the world, and that it is spreading into more temperate climates. We emphasize the importance of using DNA sequencing and genotyping to monitor the spread of parasites, and point to the necessity of further studies to improve genotypic characterization of newly recognized parasite species and strains, and their linkage to virulence. |
| first_indexed | 2024-03-10T14:59:28Z |
| format | Article |
| id | doaj.art-09b077fbf47b45819877e4d487fb8e28 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T14:59:28Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-09b077fbf47b45819877e4d487fb8e282023-11-20T20:13:43ZengMDPI AGPathogens2076-08172020-11-0191192610.3390/pathogens9110926Twenty Years of Equine Piroplasmosis Research: Global Distribution, Molecular Diagnosis, and PhylogenySharon Tirosh-Levy0Yuval Gottlieb1Lindsay M. Fry2Donald P. Knowles3Amir Steinman4Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot 7610001, IsraelKoret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot 7610001, IsraelDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164, USADepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164, USAKoret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot 7610001, IsraelEquine piroplasmosis (EP), caused by the hemoparasites <i>Theileria equi</i>, <i>Theileria haneyi</i>, and <i>Babesia caballi</i>, is an important tick-borne disease of equines that is prevalent in most parts of the world. Infection may affect animal welfare and has economic impacts related to limitations in horse transport between endemic and non-endemic regions, reduced performance of sport horses and treatment costs. Here, we analyzed the epidemiological, serological, and molecular diagnostic data published in the last 20 years, and all DNA sequences submitted to GenBank database, to describe the current global prevalence of these parasites. We demonstrate that EP is endemic in most parts of the world, and that it is spreading into more temperate climates. We emphasize the importance of using DNA sequencing and genotyping to monitor the spread of parasites, and point to the necessity of further studies to improve genotypic characterization of newly recognized parasite species and strains, and their linkage to virulence.https://www.mdpi.com/2076-0817/9/11/926equine piroplasmosis<i>Theileria equi</i>Babesia caballiequinegenotyping |
| spellingShingle | Sharon Tirosh-Levy Yuval Gottlieb Lindsay M. Fry Donald P. Knowles Amir Steinman Twenty Years of Equine Piroplasmosis Research: Global Distribution, Molecular Diagnosis, and Phylogeny Pathogens equine piroplasmosis <i>Theileria equi</i> Babesia caballi equine genotyping |
| title | Twenty Years of Equine Piroplasmosis Research: Global Distribution, Molecular Diagnosis, and Phylogeny |
| title_full | Twenty Years of Equine Piroplasmosis Research: Global Distribution, Molecular Diagnosis, and Phylogeny |
| title_fullStr | Twenty Years of Equine Piroplasmosis Research: Global Distribution, Molecular Diagnosis, and Phylogeny |
| title_full_unstemmed | Twenty Years of Equine Piroplasmosis Research: Global Distribution, Molecular Diagnosis, and Phylogeny |
| title_short | Twenty Years of Equine Piroplasmosis Research: Global Distribution, Molecular Diagnosis, and Phylogeny |
| title_sort | twenty years of equine piroplasmosis research global distribution molecular diagnosis and phylogeny |
| topic | equine piroplasmosis <i>Theileria equi</i> Babesia caballi equine genotyping |
| url | https://www.mdpi.com/2076-0817/9/11/926 |
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