Serum cholesterol and depression: A puzzle never finished

Depression is a state of sadness, hopelessness, and discouragement. Various studies have been conducted to uncover the etiological factors involved in depression. Serum folic acid is one such factor. Many researchers have reported an inverse association between serum folic acid and depression. We di...

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Main Authors: Satish Kumar Budania, Monika Rathi, Shalini Singh, Suresh Yadav
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of the Scientific Society
Subjects:
Online Access:http://www.jscisociety.com/article.asp?issn=0974-5009;year=2015;volume=42;issue=2;spage=59;epage=61;aulast=Budania
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author Satish Kumar Budania
Monika Rathi
Shalini Singh
Suresh Yadav
author_facet Satish Kumar Budania
Monika Rathi
Shalini Singh
Suresh Yadav
author_sort Satish Kumar Budania
collection DOAJ
description Depression is a state of sadness, hopelessness, and discouragement. Various studies have been conducted to uncover the etiological factors involved in depression. Serum folic acid is one such factor. Many researchers have reported an inverse association between serum folic acid and depression. We did an extensive computerized database searches on PubMed, Medline, and EBSCO and found that low serum folic acid are associated with depression, not only in adults, but also in elderly and diabetic patients. Further augmentation of folic acid with antidepressant treatment also improves the treatment outcome in depressed patients. Hence, considering the high benefits to the adverse effects ratio of serum folic acid, its supplementation should be done in "at risk" population whenever possible.
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spelling doaj.art-09b13c8e97d34dd9a2a4b4a4e8154ba72022-12-22T01:03:48ZengWolters Kluwer Medknow PublicationsJournal of the Scientific Society0974-50092015-01-01422596110.4103/0974-5009.157023Serum cholesterol and depression: A puzzle never finishedSatish Kumar BudaniaMonika RathiShalini SinghSuresh YadavDepression is a state of sadness, hopelessness, and discouragement. Various studies have been conducted to uncover the etiological factors involved in depression. Serum folic acid is one such factor. Many researchers have reported an inverse association between serum folic acid and depression. We did an extensive computerized database searches on PubMed, Medline, and EBSCO and found that low serum folic acid are associated with depression, not only in adults, but also in elderly and diabetic patients. Further augmentation of folic acid with antidepressant treatment also improves the treatment outcome in depressed patients. Hence, considering the high benefits to the adverse effects ratio of serum folic acid, its supplementation should be done in "at risk" population whenever possible.http://www.jscisociety.com/article.asp?issn=0974-5009;year=2015;volume=42;issue=2;spage=59;epage=61;aulast=BudaniaDepressionpregnancyserum folic acid
spellingShingle Satish Kumar Budania
Monika Rathi
Shalini Singh
Suresh Yadav
Serum cholesterol and depression: A puzzle never finished
Journal of the Scientific Society
Depression
pregnancy
serum folic acid
title Serum cholesterol and depression: A puzzle never finished
title_full Serum cholesterol and depression: A puzzle never finished
title_fullStr Serum cholesterol and depression: A puzzle never finished
title_full_unstemmed Serum cholesterol and depression: A puzzle never finished
title_short Serum cholesterol and depression: A puzzle never finished
title_sort serum cholesterol and depression a puzzle never finished
topic Depression
pregnancy
serum folic acid
url http://www.jscisociety.com/article.asp?issn=0974-5009;year=2015;volume=42;issue=2;spage=59;epage=61;aulast=Budania
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