Natural Biflavonoids Modulate Macrophage–Oxidized LDL Interaction In Vitro and Promote Atheroprotection In Vivo

Natural Biflavonoids Modulate Macrophage–Oxidized LDL Interaction In Vitro and Promote Atheroprotection In Vivo

The accumulation of oxidized ApoB-100-containing lipoproteins in the vascular intima and its subsequent recognition by macrophages results in foam cell formation and inflammation, key events during atherosclerosis development. Agents targeting this process are considered potentially atheroprotective...

Full description

Bibliographic Details
Main Authors:	Jorge H. Tabares-Guevara, Oscar J. Lara-Guzmán, Julian A. Londoño-Londoño, Jelver A. Sierra, Yudy M. León-Varela, Rafael M. Álvarez-Quintero, Edison J. Osorio, José R. Ramirez-Pineda
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-08-01
Series:	Frontiers in Immunology
Subjects:	atherosclerosis oxidized LDL macrophage foam cell biflavonoid morelloflavone
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00923/full

Similar Items

BIFLAVONOID COMPOUND FROM THE STEM BARK OF GAMBOGE (<i>Garcinia xanthochymus</i>)
by: Muharni Muharni, et al.
Published: (2011-11-01)

Insights into the Molecular Mechanisms of Eg5 Inhibition by (+)-Morelloflavone
by: Tomisin Happy Ogunwa, et al.
Published: (2019-04-01)

Ocorrência de biflavonoides em Clusiaceae: aspectos químicos e farmacológicos
by: Rafaela Oliveira Ferreira, et al.
Published: (2012-01-01)

Proceedings of Chemistry, Pharmacology, Pharmacokinetics and Synthesis of Biflavonoids
by: Xinqian He, et al.
Published: (2021-10-01)

Biflavonoids inhibit the production of aflatoxin by Aspergillus flavus
by: E. Gonçalez, et al.
Published: (2001-11-01)

Comprehensive characterization and antioxidant activities of the main biflavonoids of Garcinia madruno: A novel tropical species for developing functional products
by: Luis Carrillo-Hormaza, et al.
Published: (2016-12-01)

Advances in the Anti-Tumor Activity of Biflavonoids in <i>Selaginella</i>
by: Mengdie Ren, et al.
Published: (2023-04-01)

A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid
by: Sheng Yu, et al.
Published: (2017-02-01)

Naturally Occurring Cytotoxic [3′→8″]-Biflavonoids from Podocarpus nakaii
by: Pen-Ho Yeh, et al.
Published: (2012-07-01)

Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from <i>Oxytropis chiliophylla</i>
by: Yang Liu, et al.
Published: (2019-04-01)

A Purified Biflavonoid Extract From Selaginella moellendorffii Alleviates Gout Arthritis via NLRP3/ASC/Caspase-1 Axis Suppression
by: Xueyan Zhang, et al.
Published: (2021-05-01)

DNA topoisomerase inhibitors: biflavonoids from Ouratea species
by: N.F. Grynberg, et al.
Published: (2002-07-01)

Anticancer Effects of Five Biflavonoids from <i>Ginkgo Biloba</i> L. Male Flowers In Vitro
by: Min Li, et al.
Published: (2019-04-01)

Biflavonoids: Important Contributions to the Health Benefits of Ginkgo (<i>Ginkgo biloba</i> L.)
by: Dunja Šamec, et al.
Published: (2022-05-01)

Antioxidant potential of biflavonoid attenuates hyperglycemia by modulating the carbohydrate metabolic enzymes in high fat diet/streptozotocin induced diabetic rats
by: Sundaram Ramalingam, et al.
Published: (2020-01-01)

Antiallergic Properties of Biflavonoids Isolated from the Flowers of <em>Mesua ferrea</em> Linn.
by: Yoshiaki Manse, et al.
Published: (2022-05-01)

New Biflavonoids with α-Glucosidase and Pancreatic Lipase Inhibitory Activities from Boesenbergia rotunda
by: Nutputsorn Chatsumpun, et al.
Published: (2017-10-01)

Garcinia Biflavonoid 1 Improves Lipid Metabolism in HepG2 Cells via Regulating PPARα
by: Hai-Xin Chen, et al.
Published: (2022-03-01)

Biflavonoids from <i>Selaginella doederleinii</i> as Potential Antitumor Agents for Intervention of Non-Small Cell Lung Cancer
by: Fenghua Kang, et al.
Published: (2021-09-01)

Improved solubility, dissolution rate, and oral bioavailability of main biflavonoids from Selaginella doederleinii extract by amorphous solid dispersion
by: Bing Chen, et al.
Published: (2020-01-01)

Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages
by: Oscar J. Lara-Guzmán, et al.
Published: (2018-05-01)

Anti-tumor effect and mechanism of the total biflavonoid extract from S doederleinii on human cervical cancer cells in vitro and in vivo
by: Shilan Lin, et al.
Published: (2024-01-01)

Total biflavonoids extraction from Selaginella chaetoloma utilizing ultrasound-assisted deep eutectic solvent: Optimization of conditions, extraction mechanism, and biological activity in vitro
by: Chao Liu, et al.
Published: (2023-08-01)

Ionic Liquid–Ultrasound-Based Extraction of Biflavonoids from <i>Selaginella helvetica</i> and Investigation of Their Antioxidant Activity
by: Yongmei Jiang, et al.
Published: (2018-12-01)

Strong and Selective Inhibitory Effects of the Biflavonoid Selamariscina A against CYP2C8 and CYP2C9 Enzyme Activities in Human Liver Microsomes
by: So-Young Park, et al.
Published: (2020-04-01)

Preussianone, a New Flavanone-Chromone Biflavonoid from <em>Garcinia preussii</em> Engl.
by: Gerhard Bringmann, et al.
Published: (2012-05-01)

Phytochemical Composition of Selaginella spp. from Java Island Indonesia
by: Tatik Chikmawati, et al.
Published: (2012-08-01)

Influence of LDL apheresis on LDL subtypes in patients with coronary heart disease and severe hyperlipoproteinemia
by: B.M. Schamberger, et al.
Published: (2000-05-01)

New 3′,8′′-Linked Biflavonoids from Selaginella uncinata Displaying Protective Effect against Anoxia
by: Ming Fan, et al.
Published: (2011-07-01)

Preparative Isolation of Two Prenylated Biflavonoids from the Roots and Rhizomes of Sinopodophyllum emodi by Sephadex LH-20 Column and High-Speed Counter-Current Chromatography
by: Yan-Jun Sun, et al.
Published: (2015-12-01)

A Biflavonoid-Rich Extract from <i>Selaginella doederleinii</i> Hieron. against Throat Carcinoma via Akt/Bad and IKKβ/NF-κB/COX-2 Pathways
by: Sisi Wang, et al.
Published: (2022-12-01)

Density distribution of electronegative LDL in normolipemic and hyperlipemic subjects
by: José Luis Sánchez-Quesada, et al.
Published: (2002-05-01)

Toxicodendron succedaneum (L.) Kuntze (Japanese wax tree): A review on its phytochemistry, pharmacology, and toxicity
by: Shailendra S. Gurav, et al.
Published: (2022-09-01)

In vitro antibacterial activity of Loxostylis alata extracts and isolated compounds against Salmonella species
by: Dorcas A. Gado, et al.
Published: (2021-04-01)

Electronegative LDL Is Associated with Plaque Vulnerability in Patients with Ischemic Stroke and Carotid Atherosclerosis
by: Núria Puig, et al.
Published: (2023-02-01)

Analysis of the Total Biflavonoids Extract from Selaginella doederleinii by HPLC-QTOF-MS and Its In Vitro and In Vivo Anticancer Effects
by: Hong Yao, et al.
Published: (2017-02-01)

Okside-LDL ve Reseptörü Lektin Benzeri Ox-LDL Reseptör-1
by: Ümmügülsüm Can
Published: (2016-12-01)

Serum ox-LDL Level is Reduced with the Extent of Stenosis in Coronary Arteries
by: Mohammad Najafi, et al.
Published: (2013-05-01)

High-Fat Diet Increases Serum HDL, but Not for LDL and HDL/LDL Ratio in MICE
by: Iqbal Laksana, et al.
Published: (2021-06-01)

Neuroprotective Potential of Biflavone Ginkgetin: A Review
by: İ. İrem Tatlı Çankaya, et al.
Published: (2023-02-01)