Effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopia
Abstract To investigate the factors for treatment success in anisometropic amblyopia according to the spherical equivalent (SE) type of amblyopic eyes. Medical records of 397 children with anisometropic amblyopia aged 3 to 12 years who presented in a secondary referral eye hospital during 2010 ~ 201...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-11-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-01377-1 |
| _version_ | 1818913770827677696 |
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| author | Daye Diana Choi Dae Hee Kim Ungsoo Samuel Kim Seung-Hee Baek |
| author_facet | Daye Diana Choi Dae Hee Kim Ungsoo Samuel Kim Seung-Hee Baek |
| author_sort | Daye Diana Choi |
| collection | DOAJ |
| description | Abstract To investigate the factors for treatment success in anisometropic amblyopia according to the spherical equivalent (SE) type of amblyopic eyes. Medical records of 397 children with anisometropic amblyopia aged 3 to 12 years who presented in a secondary referral eye hospital during 2010 ~ 2016 were retrospectively reviewed. Anisometropia was defined as ≥ 1 diopter (D) difference in SE, or ≥ 1.5 D difference of cylindrical error between the eyes. According to the SE of amblyopic eyes, patients were categorized into hyperopia (SE ≥ 1D), emmetropia (− 1 < SE < + 1) and myopia (SE ≤ − 1D) groups. Treatment success was defined as achieving interocular logMAR visual acuity difference < 0.2. Multivariate logistic regression was used to analyze the factors for treatment success. Significant factors for the amblyopia treatment success in hyperopia group (n = 270) were younger age [adjusted odds ratio (aOR) (95% confidence interval, CI) = 0.529 (0.353, 0.792)], better BCVA in amblyopic eyes at presentation [aOR (95% CI) 0.004 (0, 0.096)], longer follow-up period [aOR (95%CI) = 1.098 (1.036, 1.162)], and no previous amblyopia treatment history [aOR (95% CI) 0.059 (0.010, 0.364)]. In myopia group (n = 68), younger age [aOR (95% CI) 0.440 (0.208, 0.928)] and better BCVA in amblyopic eyes [aOR (95% CI) 0.034 (0.003, 0.469)] were associated with higher odds of treatment success. There was no significant factor for treatment success in emmetropia group (n = 59) in this population. The refractive error type of amblyopic eyes at presentation affects the factors for treatment success in anisometropic amblyopia. |
| first_indexed | 2024-12-19T23:35:46Z |
| format | Article |
| id | doaj.art-09b19de0d7bc4d75aba738856764aee5 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-19T23:35:46Z |
| publishDate | 2021-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-09b19de0d7bc4d75aba738856764aee52022-12-21T20:01:36ZengNature PortfolioScientific Reports2045-23222021-11-011111810.1038/s41598-021-01377-1Effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopiaDaye Diana Choi0Dae Hee Kim1Ungsoo Samuel Kim2Seung-Hee Baek3Department of Ophthalmology, Strabismus & Pediatric Ophthalmology Center, Kim’s Eye HospitalDepartment of Ophthalmology, Strabismus & Pediatric Ophthalmology Center, Kim’s Eye HospitalDepartment of Ophthalmology, Strabismus & Pediatric Ophthalmology Center, Kim’s Eye HospitalDepartment of Ophthalmology, Strabismus & Pediatric Ophthalmology Center, Kim’s Eye HospitalAbstract To investigate the factors for treatment success in anisometropic amblyopia according to the spherical equivalent (SE) type of amblyopic eyes. Medical records of 397 children with anisometropic amblyopia aged 3 to 12 years who presented in a secondary referral eye hospital during 2010 ~ 2016 were retrospectively reviewed. Anisometropia was defined as ≥ 1 diopter (D) difference in SE, or ≥ 1.5 D difference of cylindrical error between the eyes. According to the SE of amblyopic eyes, patients were categorized into hyperopia (SE ≥ 1D), emmetropia (− 1 < SE < + 1) and myopia (SE ≤ − 1D) groups. Treatment success was defined as achieving interocular logMAR visual acuity difference < 0.2. Multivariate logistic regression was used to analyze the factors for treatment success. Significant factors for the amblyopia treatment success in hyperopia group (n = 270) were younger age [adjusted odds ratio (aOR) (95% confidence interval, CI) = 0.529 (0.353, 0.792)], better BCVA in amblyopic eyes at presentation [aOR (95% CI) 0.004 (0, 0.096)], longer follow-up period [aOR (95%CI) = 1.098 (1.036, 1.162)], and no previous amblyopia treatment history [aOR (95% CI) 0.059 (0.010, 0.364)]. In myopia group (n = 68), younger age [aOR (95% CI) 0.440 (0.208, 0.928)] and better BCVA in amblyopic eyes [aOR (95% CI) 0.034 (0.003, 0.469)] were associated with higher odds of treatment success. There was no significant factor for treatment success in emmetropia group (n = 59) in this population. The refractive error type of amblyopic eyes at presentation affects the factors for treatment success in anisometropic amblyopia.https://doi.org/10.1038/s41598-021-01377-1 |
| spellingShingle | Daye Diana Choi Dae Hee Kim Ungsoo Samuel Kim Seung-Hee Baek Effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopia Scientific Reports |
| title | Effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopia |
| title_full | Effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopia |
| title_fullStr | Effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopia |
| title_full_unstemmed | Effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopia |
| title_short | Effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopia |
| title_sort | effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopia |
| url | https://doi.org/10.1038/s41598-021-01377-1 |
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