Decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity: Effects of -6 degree head-down tilt bed rest
Space is characterized by risk and uncertainty. As humans play an important role in long-duration space missions, the ability to make risky decisions effectively is important for astronauts who spend extended time periods in space. The present study used the Balloon Analog Risk Task to conduct both...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-05-01
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| Series: | Frontiers in Behavioral Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00187/full |
| _version_ | 1811265236631552000 |
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| author | Li-Lin eRao Yuan eZhou Zhu-Yuan eLiang Hengyi eRao Rui eZheng Yan eSun Cheng eTan Zhi-Qiang eTian Xiao-Ping eChen Chun-Hui eWang Yan-Qiang eBai Shan-Guang eChen Shu eLi |
| author_facet | Li-Lin eRao Yuan eZhou Zhu-Yuan eLiang Hengyi eRao Rui eZheng Yan eSun Cheng eTan Zhi-Qiang eTian Xiao-Ping eChen Chun-Hui eWang Yan-Qiang eBai Shan-Guang eChen Shu eLi |
| author_sort | Li-Lin eRao |
| collection | DOAJ |
| description | Space is characterized by risk and uncertainty. As humans play an important role in long-duration space missions, the ability to make risky decisions effectively is important for astronauts who spend extended time periods in space. The present study used the Balloon Analog Risk Task to conduct both behavioral and fMRI experiments to evaluate the effects of simulated microgravity on individuals’ risk-taking behavior and the neural basis of the effect. The results showed that participants’ risk-taking behavior was not affected by bed rest. However, we found that the ventromedial prefrontal cortex (VMPFC) showed less deactivation after bed rest and that the VMPFC activation in the active choice condition showed no significant difference between the win outcome and the loss outcome after bed rest, although its activation was significantly greater in the win outcome than in the loss outcome before bed rest. These results suggested that the participants showed a decreased level of value calculation after the bed rest. Our findings can contribute to a better understanding of the effect of microgravity on individual higher-level cognitive functioning. |
| first_indexed | 2024-04-12T20:20:02Z |
| format | Article |
| id | doaj.art-09b3ce2e97ae42e5ae8f7c48cad6a6da |
| institution | Directory Open Access Journal |
| issn | 1662-5153 |
| language | English |
| last_indexed | 2024-04-12T20:20:02Z |
| publishDate | 2014-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Behavioral Neuroscience |
| spelling | doaj.art-09b3ce2e97ae42e5ae8f7c48cad6a6da2022-12-22T03:18:01ZengFrontiers Media S.A.Frontiers in Behavioral Neuroscience1662-51532014-05-01810.3389/fnbeh.2014.0018778501Decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity: Effects of -6 degree head-down tilt bed restLi-Lin eRao0Yuan eZhou1Zhu-Yuan eLiang2Hengyi eRao3Rui eZheng4Yan eSun5Cheng eTan6Zhi-Qiang eTian7Xiao-Ping eChen8Chun-Hui eWang9Yan-Qiang eBai10Shan-Guang eChen11Shu eLi12Institute of Psychology, Chinese Academy of SciencesInstitute of Psychology, Chinese Academy of SciencesInstitute of Psychology, Chinese Academy of SciencesSun Yat-Sen UniversityInstitute of Psychology, Chinese Academy of SciencesInstitute of Psychology, Chinese Academy of SciencesChina Astronaut Research and Training CenterChina Astronaut Research and Training CenterChina Astronaut Research and Training CenterChina Astronaut Research and Training CenterChina Astronaut Research and Training CenterChina Astronaut Research and Training CenterInstitute of Psychology, Chinese Academy of SciencesSpace is characterized by risk and uncertainty. As humans play an important role in long-duration space missions, the ability to make risky decisions effectively is important for astronauts who spend extended time periods in space. The present study used the Balloon Analog Risk Task to conduct both behavioral and fMRI experiments to evaluate the effects of simulated microgravity on individuals’ risk-taking behavior and the neural basis of the effect. The results showed that participants’ risk-taking behavior was not affected by bed rest. However, we found that the ventromedial prefrontal cortex (VMPFC) showed less deactivation after bed rest and that the VMPFC activation in the active choice condition showed no significant difference between the win outcome and the loss outcome after bed rest, although its activation was significantly greater in the win outcome than in the loss outcome before bed rest. These results suggested that the participants showed a decreased level of value calculation after the bed rest. Our findings can contribute to a better understanding of the effect of microgravity on individual higher-level cognitive functioning.http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00187/fullBed RestfMRIriskBARTventromedial prefrontal cortex |
| spellingShingle | Li-Lin eRao Yuan eZhou Zhu-Yuan eLiang Hengyi eRao Rui eZheng Yan eSun Cheng eTan Zhi-Qiang eTian Xiao-Ping eChen Chun-Hui eWang Yan-Qiang eBai Shan-Guang eChen Shu eLi Decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity: Effects of -6 degree head-down tilt bed rest Frontiers in Behavioral Neuroscience Bed Rest fMRI risk BART ventromedial prefrontal cortex |
| title | Decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity: Effects of -6 degree head-down tilt bed rest |
| title_full | Decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity: Effects of -6 degree head-down tilt bed rest |
| title_fullStr | Decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity: Effects of -6 degree head-down tilt bed rest |
| title_full_unstemmed | Decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity: Effects of -6 degree head-down tilt bed rest |
| title_short | Decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity: Effects of -6 degree head-down tilt bed rest |
| title_sort | decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity effects of 6 degree head down tilt bed rest |
| topic | Bed Rest fMRI risk BART ventromedial prefrontal cortex |
| url | http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00187/full |
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