The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment
Lung cancer is the most lethal cancer: it has a significant incidence and low survival rates. Lifestyle has an important influence on cancer onset and its progression, indeed environmental factors and smoke are involved in cancer establishment, and in lung cancer. Physical activity is a determinant...
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-05-01
|
| Series: | Life |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-1729/12/6/782 |
| _version_ | 1827659205009473536 |
|---|---|
| author | Gaetana Messina Nicola Tartaglia Antonio Ambrosi Chiara Porro Angelo Campanozzi Anna Valenzano Gaetano Corso Alfonso Fiorelli Rita Polito Mario Santini Marcellino Monda Domenico Tafuri Giovanni Messina Antonietta Messina Vincenzo Monda |
| author_facet | Gaetana Messina Nicola Tartaglia Antonio Ambrosi Chiara Porro Angelo Campanozzi Anna Valenzano Gaetano Corso Alfonso Fiorelli Rita Polito Mario Santini Marcellino Monda Domenico Tafuri Giovanni Messina Antonietta Messina Vincenzo Monda |
| author_sort | Gaetana Messina |
| collection | DOAJ |
| description | Lung cancer is the most lethal cancer: it has a significant incidence and low survival rates. Lifestyle has an important influence on cancer onset and its progression, indeed environmental factors and smoke are involved in cancer establishment, and in lung cancer. Physical activity is a determinant in inhibiting or slowing lung cancer. Certainly, the inflammation is a major factor responsible for lung cancer establishment. In this scenario, regular physical activity can induce anti-inflammatory effects, reducing ROS production and stimulating immune cell system activity. On lung function, physical activity improves lung muscle strength, FEV1 and forced vital capacity. In lung cancer patients, it reduces dyspnea, fatigue and pain. Data in the literature has shown the effects of physical activity both in in vivo and in vitro studies, reporting that its anti-inflammatory action is determinant in the onset of human diseases such as lung cancer. It has a beneficial effect not only in the prevention of lung cancer, but also on treatment and prognosis. For these reasons, it is retained as an adjuvant in lung cancer treatment both for the administration and prognosis of this type of cancer. The purpose of this review is to analyze the role of physical activity in lung cancer and to recommend regular physical activity and lifestyle changes to prevent or treat this pathology. |
| first_indexed | 2024-03-09T23:16:15Z |
| format | Article |
| id | doaj.art-09b67312e9ac423a992577cc0fd1fc53 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T23:16:15Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-09b67312e9ac423a992577cc0fd1fc532023-11-23T17:35:22ZengMDPI AGLife2075-17292022-05-0112678210.3390/life12060782The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or TreatmentGaetana Messina0Nicola Tartaglia1Antonio Ambrosi2Chiara Porro3Angelo Campanozzi4Anna Valenzano5Gaetano Corso6Alfonso Fiorelli7Rita Polito8Mario Santini9Marcellino Monda10Domenico Tafuri11Giovanni Messina12Antonietta Messina13Vincenzo Monda14Department of Translational Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, 80138 Naples, ItalyDepartment of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, ItalyDepartment of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, ItalyDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, ItalyDepartment of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, ItalyDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, ItalyDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, ItalyDepartment of Translational Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, 80138 Naples, ItalyDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, ItalyDepartment of Translational Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, 80138 Naples, ItalyDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetics and Sports Medicine, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyClinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Università degli Studi della Campania, Luigi Vanvitelli, 81100 Naples, ItalyDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, ItalyDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetics and Sports Medicine, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetics and Sports Medicine, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyLung cancer is the most lethal cancer: it has a significant incidence and low survival rates. Lifestyle has an important influence on cancer onset and its progression, indeed environmental factors and smoke are involved in cancer establishment, and in lung cancer. Physical activity is a determinant in inhibiting or slowing lung cancer. Certainly, the inflammation is a major factor responsible for lung cancer establishment. In this scenario, regular physical activity can induce anti-inflammatory effects, reducing ROS production and stimulating immune cell system activity. On lung function, physical activity improves lung muscle strength, FEV1 and forced vital capacity. In lung cancer patients, it reduces dyspnea, fatigue and pain. Data in the literature has shown the effects of physical activity both in in vivo and in vitro studies, reporting that its anti-inflammatory action is determinant in the onset of human diseases such as lung cancer. It has a beneficial effect not only in the prevention of lung cancer, but also on treatment and prognosis. For these reasons, it is retained as an adjuvant in lung cancer treatment both for the administration and prognosis of this type of cancer. The purpose of this review is to analyze the role of physical activity in lung cancer and to recommend regular physical activity and lifestyle changes to prevent or treat this pathology.https://www.mdpi.com/2075-1729/12/6/782lung cancerhealthy lifestylephysical activityoxidative stressinflammationlung cancer treatment |
| spellingShingle | Gaetana Messina Nicola Tartaglia Antonio Ambrosi Chiara Porro Angelo Campanozzi Anna Valenzano Gaetano Corso Alfonso Fiorelli Rita Polito Mario Santini Marcellino Monda Domenico Tafuri Giovanni Messina Antonietta Messina Vincenzo Monda The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment Life lung cancer healthy lifestyle physical activity oxidative stress inflammation lung cancer treatment |
| title | The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment |
| title_full | The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment |
| title_fullStr | The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment |
| title_full_unstemmed | The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment |
| title_short | The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment |
| title_sort | beneficial effects of physical activity in lung cancer prevention and or treatment |
| topic | lung cancer healthy lifestyle physical activity oxidative stress inflammation lung cancer treatment |
| url | https://www.mdpi.com/2075-1729/12/6/782 |
| work_keys_str_mv | AT gaetanamessina thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT nicolatartaglia thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT antonioambrosi thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT chiaraporro thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT angelocampanozzi thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT annavalenzano thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT gaetanocorso thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT alfonsofiorelli thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT ritapolito thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT mariosantini thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT marcellinomonda thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT domenicotafuri thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT giovannimessina thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT antoniettamessina thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT vincenzomonda thebeneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT gaetanamessina beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT nicolatartaglia beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT antonioambrosi beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT chiaraporro beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT angelocampanozzi beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT annavalenzano beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT gaetanocorso beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT alfonsofiorelli beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT ritapolito beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT mariosantini beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT marcellinomonda beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT domenicotafuri beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT giovannimessina beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT antoniettamessina beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment AT vincenzomonda beneficialeffectsofphysicalactivityinlungcancerpreventionandortreatment |